Protein Alignment CG5397 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 654
• Identity: 173/654 - (26%)
• Similarity: 261/654 - (39%)
• Gaps: 177/654 - (27%)

  Fly    12 LLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIYSF 76
            |:.||   ||:|.:.|             ...:|||.: .:..::..:...:|||..|   :..|
Mouse     6 LIWLS---LAACTAWG-------------YPSSPPVVN-TVKGKVLGKYVNLEGFTQP---VAVF 50

  Fly    77 LGMHYAEPPVGPLRYSRP-------VYKRLAGDFNATKHGPPCIQP-------HPQFPQR----- 122
            ||:.:|:||:|.||::.|       ..|      |.|.:.|.|.|.       ...|..|
Mouse    51 LGVPFAKPPLGSLRFAPPQPAEPWSFVK------NTTSYPPMCSQDAVGGQVLSELFTNRKENIP 109

  Fly   123 IIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPM-AQRGAIVVAPQYRLGS 186
            :...||||.||:|||....:.:.|||.||||.||...|.|:.||...: |....:||..|||||.
Mouse   110 LQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLGI 174

  Fly   187 LGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSA 251
            .|....|.:...||....|..||||||.|.|:.|||||..|...|..:|..|...|.:||.:::.
Mouse   175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNL 239

  Fly   252 GDVHGVVAMSGTALSQ--YAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKV 314
              .|..::.||.:|:.  ...|.:|:..:  ||.::||.|.....:|:|||.|:.:::::...|:
Mouse   240 --FHRAISESGVSLTAALITTDVKPIAGL--VATLSGCKTTTSAVMVHCLRQKTEDELLETSLKL 300

  Fly   315 QTERLAGRALVKGLTGN-VGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHE- 377
            ...:|       .|.|| ....|.:.:..||..||.    .||:.|...:||.:|.:.|:.|.|
Mouse   301 NLFKL-------DLLGNPKESYPFLPTVIDGVVLPK----APEEILAEKSFSTVPYIVGINKQEF 354

  Fly   378 --------------------TANSV------TVETIEKVFG-SAEQFLGSLSDSLNKLTSFLKID 415
                                ||||:      |::..|.:.. .||::||...|...|...|
Mouse   355 GWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLF---- 415

  Fly   416 KLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRL- 479
                                  ||:                   ..||:|.:|:|:.::.....
Mouse   416 ----------------------QDL-------------------MADVVFGVPSVIVSRSHRDAG 439

  Fly   480 APAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETV--GHGDEIGYMFDANDIFGNPM----- 537
            |..:||.|||..      :|:..:         :|:.|  .|||||      ..:||:|.
Mouse   440 ASTYMYEFEYRP------SFVSAM---------RPKAVIGDHGDEI------FSVFGSPFLKDGA 483

  Fly   538 --EETRLTSAEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRF 600
              |||.|:..        ::.....||......||....:.....| ..::||....|.:...:.
Mouse   484 SEEETNLSKM--------VMKFWANFARNGNPNGGGLPHWPEYDQK-EGYLKIGASTQAAQRLKD 539

  Fly   601 CELS 604
            .|:|
Mouse   540 KEVS 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	161/598 (27%)
		Aes	82..>261	CDD:223730	71/198 (36%)
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	165/620 (27%)
		Aes	<121..>239	CDD:223730	49/117 (42%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910