Protein Alignment CG5397 and Ces2

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001258232.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 157/570 - (27%)
• Similarity: 229/570 - (40%)
• Gaps: 125/570 - (21%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIY 74
            |||||:.|                       |.:..|...|:..........:::..::...|::
  Rat    17 LLLLLIHV-----------------------QGQDSPESSPIRTTHTGQVQGKLDHVKDTKAGVH 58

  Fly    75 SFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQ-----------PHPQFPQRIIGDE 127
            :|||:.:|:|||||||::.| ..:..:|..:||.....|:|           ........|...|
  Rat    59 TFLGIPFAKPPVGPLRFAPPEPPEPWSGVRDATSQPAMCLQNLDILDEVGLLDMKMILSSISMSE 123

  Fly   128 DCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPM-AQRGAIVVAPQYRLGSLGIMG 191
            |||.||||.|....|.:.|||.||||.|....|.|:.||.:.: .....:||..|||||.||...
  Rat   124 DCLYLNVYAPAHAREGSNLPVMVWIHGGALVVGMASMYDGSLLTVNEDLVVVTIQYRLGVLGFFS 188

  Fly   192 DGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHG 256
            .|.:...||....|..||||||...|::|||||.:|...|..:|..|.....:||.|:  |..||
  Rat   189 TGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVISPMSQ--GLFHG 251

  Fly   257 VVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAG 321
            .:..||.||....:.:........|||::||...:...:|.|||:||..:|
  Rat   252 AIMESGVALLPDLISETSETVSTTVAKLSGCEAMDSEALVRCLRAKSGAEI-------------- 302

  Fly   322 RALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVET 386
                  |..|..|: .|.:..||..||.    .|::.|.|.:|..:|.:.||...|...     |
  Rat   303 ------LVINKVFK-MIPAVVDGEFLPR----HPKELLASEDFHPVPSIIGVNTDEYCC-----T 351

  Fly   387 IEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQA--LNV 449
            |..|.|:| |.:..||..                       .|.:||..|...:...|:.  |.:
  Rat   352 IPMVMGTA-QIIKELSRE-----------------------NLQAVLKDTAAQMMLPPECGDLLM 392

  Fly   450 DQVLSKVVESTT----------DVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGLP 504
            ::.:....:|.|          |.||.:||:.........||.:.|.|::..:..|.:
  Rat   393 EEYMGNTDDSQTLQIQYTEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNV------- 450

  Fly   505 IVSETAHDKPETVGHGDEIGYMFDANDIFGNPM-----EETRLTSAEDLK 549
               ...|.|.:   |.||:.::|.:   |.:.|     ||.||.|...:|
  Rat   451 ---RPPHVKAD---HADEVPFVFGS---FFSGMKLDFTEEERLLSRRMMK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	148/518 (29%)
		Aes	82..>261	CDD:223730	72/191 (38%)
Ces2	NP_001258232.1	COesterase	31..540	CDD:278561	149/533 (28%)
		Aes	<130..>233	CDD:223730	43/102 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900