Protein Alignment CG5397 and Ces2

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 157/570 - (27%)
• Similarity: 229/570 - (40%)
• Gaps: 125/570 - (21%)

  Fly    10 LLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIY 74
            |||||:.|                       |.:..|...|:..........:::..::...|::
  Rat    17 LLLLLIHV-----------------------QGQDSPESSPIRTTHTGQVQGKLDHVKDTKAGVH 58

  Fly    75 SFLGMHYAEPPVGPLRYSRP-VYKRLAGDFNATKHGPPCIQ-----------PHPQFPQRIIGDE 127
            :|||:.:|:|||||||::.| ..:..:|..:||.....|:|           ........|...|
  Rat    59 TFLGIPFAKPPVGPLRFAPPEPPEPWSGVRDATSQPAMCLQNLDILDEVGLLDMKMILSSISMSE 123

  Fly   128 DCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPM-AQRGAIVVAPQYRLGSLGIMG 191
            |||.||||.|....|.:.|||.||||.|....|.|:.||.:.: .....:||..|||||.||...
  Rat   124 DCLYLNVYAPAHAREGSNLPVMVWIHGGALVVGMASMYDGSLLTVNEDLVVVTIQYRLGVLGFFS 188

  Fly   192 DGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHG 256
            .|.:...||....|..||||||...|::|||||.:|...|..:|..|.....:||.|:  |..||
  Rat   189 TGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVISPMSQ--GLFHG 251

  Fly   257 VVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAG 321
            .:..||.||....:.:........|||::||...:...:|.|||:||..:|
  Rat   252 AIMESGVALLPDLISETSETVSTTVAKLSGCEAMDSEALVRCLRAKSGAEI-------------- 302

  Fly   322 RALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVET 386
                  |..|..|: .|.:..||..||.    .|::.|.|.:|..:|.:.||...|...     |
  Rat   303 ------LVINKVFK-MIPAVVDGEFLPR----HPKELLASEDFHPVPSIIGVNTDEYCC-----T 351

  Fly   387 IEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQA--LNV 449
            |..|.|:| |.:..||..                       .|.:||..|...:...|:.  |.:
  Rat   352 IPMVMGTA-QIIKELSRE-----------------------NLQAVLKDTAAQMMLPPECGDLLM 392

  Fly   450 DQVLSKVVESTT----------DVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGLP 504
            ::.:....:|.|          |.||.:||:.........||.:.|.|::..:..|.:
  Rat   393 EEYMGNTDDSQTLQIQYTEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNV------- 450

  Fly   505 IVSETAHDKPETVGHGDEIGYMFDANDIFGNPM-----EETRLTSAEDLK 549
               ...|.|.:   |.||:.::|.:   |.:.|     ||.||.|...:|
  Rat   451 ---RPPHVKAD---HADEVPFVFGS---FFSGMKLDFTEEERLLSRRMMK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	149/532 (28%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	149/532 (28%)