Protein Alignment CG5397 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 648
• Identity: 160/648 - (24%)
• Similarity: 254/648 - (39%)
• Gaps: 177/648 - (27%)

  Fly    49 DPVIFARLFDRDARVEGFR----NPSTG-IYSFLGMHYAEPPVGPLRYSRPVYKRLAGDF-NATK 107
            |||:....    .:|.||:    |...| :..|||:.||.||:|..|:..|....:.||. |:|:
 Frog    52 DPVVLTTY----GKVRGFKKELNNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKNSTQ 112

  Fly   108 HGPPCIQPHPQFPQRIIG--------------------------DEDCLLLNVYTP--------- 137
            ..|.|       ||.|:|                          .||||.||:|.|
 Frog   113 FAPVC-------PQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISK 170

  Fly   138 ----------------------------------QMPDETTGLPVFVWIHPGGYRYGSAAQYDAT 168
                                              .:.|.....||.|:||.|.|..|:...:|.:
 Frog   171 ECARKPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGS 235

  Fly   169 PMAQRG-AIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGH 232
            .:|..| .||:...||||.||.:..|.:...||..:.||..||||.::.|.:|||:|.::...|.
 Frog   236 VLASYGNVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 300

  Fly   233 GSGAASAMYLSMSPTS---RSAGDVHGV----VAMSGTALSQYAMDKEPVQSVQEVAKINGCPTG 290
            |:||:....|::|..|   |.:....|:    :|.||||||.:|:..:|.:..:.:|...||...
 Frog   301 GAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNMS 365

  Fly   291 NELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEP 355
            :..|:|.||:.|...:::  |..:|..|.           ::.|.|.|    ||..:|.    :|
 Frog   366 DSGELVECLQKKPYRELV--DQDIQPVRY-----------HIAFGPVI----DGDVIPD----DP 409

  Fly   356 EQQLKSSNFSGIPLLTGVTKHETANSV--TVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLT 418
            :..::...|....::.||.:.|....|  ||:..:.|         |.||....:::|  :|.|.
 Frog   410 QVLMEQGEFLNYDIMLGVNQGEGLKFVESTVDHEDGV---------SSSDFDFAVSNF--VDNLY 463

  Fly   419 GQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVEST-TDVLFNLPAVLTTQVWSRL-AP 481
            |.....:      :|..|::.::......|..:...|.:.:. ||..:..|||.|..:.|.. :|
 Frog   464 GYTEGKD------ILRETIKFMYTDWADRNNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSP 522

  Fly   482 AFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPM-EETRL--- 542
            .:.|:|.::....:       :|..::.:        |||||.|      :||.|| ..|.|
 Frog   523 TYFYAFYHHCQTDQ-------VPAWADAS--------HGDEIPY------VFGIPMIGPTELFPC 566

  Fly   543 -TSAEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELS 604
             .|..|:.:...::.....||.               ||.....:..|||...:...||.|::
 Frog   567 NFSKNDVMLSAVVMTYWTNFAK---------------TGDPNQPVPQDTKFIHTKPNRFEEVA 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	154/629 (24%)
		Aes	82..>261	CDD:223730	68/256 (27%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	160/648 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910