Protein Alignment CG5397 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_608591.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 700
• Identity: 172/700 - (24%)
• Similarity: 279/700 - (39%)
• Gaps: 183/700 - (26%)

  Fly     8 NTLLLLLLSVVI---LASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNP 69
            :|.|:.||.:.:   |:||:.......:...:..|             :.:|  |..|.| ..|.
Zfish    23 DTCLVWLLGLALRLALSSCQRADLTTAKHPMVTTG-------------YGKL--RGVRKE-LNNE 71

  Fly    70 STG-IYSFLGMHYAEPPVGPLRYSRPVYKRLAGDF----NATKHGPPCIQPHPQFPQRIIG---- 125
            ..| :..:||:.||.||||..|:..|   ...|.:    |||:..|.|       ||.|.|
Zfish    72 ILGPVEQYLGVPYATPPVGERRFQPP---EAPGSWQEIRNATQFAPVC-------PQNIHGVLPE 126

  Fly   126 ---------------------DEDCLLLNVYTP-------QMPDETT-------------GLPVF 149
                                 .||||.||||.|       :..||::             ..||.
Zfish   127 IMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVM 191

  Fly   150 VWIHPGGYRYGSAAQYDATPMAQRG-AIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWV 213
            ::||.|.:..|:...:||:.:|..| .|||...||||.||.:..|.:...||..:.|...||||:
Zfish   192 LFIHGGSFMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWL 256

  Fly   214 TDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSV 278
            .:.|.:|||:|:::...|.|:||:....|.:|  ..|.|.....:|.||:|:|.::::..|:...
Zfish   257 NENIGHFGGDPERITIFGSGAGASCVNLLILS--HHSEGLFQRAIAQSGSAISSWSVNYRPLMYT 319

  Fly   279 QEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDD 343
            :.:||..||...:..::|:|||.||..:::  |..||..|.           ::.|.|.:    |
Zfish   320 KILAKKVGCSYSDTADLVDCLRRKSYRELV--DQDVQPARY-----------HIAFGPVV----D 367

  Fly   344 GRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKL 408
            |..:|.    :||..::...|....:|.||.:.|....|.....|:.. ||..|..::|:.::.|
Zfish   368 GDVVPD----DPEILMQQGEFLNYDILLGVNQGEGLKFVDDNEGEEGI-SAASFDYTISNFVDNL 427

  Fly   409 TSFLKIDKLTGQIAKPELPGLTSVLTPTLQDV---WKVPQALNVDQVLSKVVESTTDVLFNLPAV 470
            ..:               |....:|..|::.:   |  ....|.|.....::...||..:..|||
Zfish   428 YGY---------------PEGKDILRETIKFMYTDW--ADRDNGDMRRKTLLALFTDHQWVAPAV 475

  Fly   471 LTTQVWSRL-APAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPE--TVGHGDEIGYM------ 526
            .|.::.:.. :|.:.|:|.::                .:| ..:||  ...|||||.|:
Zfish   476 ATAKLHAEFQSPVYFYTFHHH----------------CQT-EARPEWADAAHGDEIPYVFGVPMV 523

  Fly   527 ---------FDANDIFGNPMEETRLTS-----------AEDLK---VRNNLIDLLV--KFANKDK 566
                     |..|||..:.:..|..|:           .:|.|   .:.|..:.::  ||::|||
Zfish   524 GATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDK 588

  Fly   567 EE---GGKSSIFQSVTGKATPF-IKIDTKLQTSNDFRFCELSVLGASLSP 612
            :.   |.|..|..:.......| :::...|.|.:|    |:......|.|
Zfish   589 QYLHIGLKPRIRDNYRANKVAFWLELVPHLHTIHD----EIPTYTTQLPP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5397	NP_608591.1	COesterase	48..599	CDD:395084	161/642 (25%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	158/642 (25%)