DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42329 and oac-32

DIOPT Version :9

Sequence 1:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	712	Identity:	201/712 - (28%)
Similarity:	317/712 - (44%)	Gaps:	110/712 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIVALIGIMGVGVLTTAQTYSSKDLLTWMQSSNFGYQVLQQA---LNDNQSSSAAEASCLAEVRL 62
            :|:.|:.|    :.||:.|:  ||::......|...|.|...   :|..:......|.|     :
Worm     8 LIILLLNI----IPTTSATW--KDVIKPKPLDNLSAQCLNDTNTWINSLEIFGTLYAEC-----I 61

  Fly    63 LLTGAEAKSLPALR-------VFDAWGKFP-QGLLYGHFMDMGNYESCLSLDLSKSLGNVMTINA 119
            ::....||.|..||       ..||:|:|| .|||....:..|:|:.|     .:..|....:|
Worm    62 IMKKCNAKELKVLRDNLYAVQQLDAFGQFPGAGLLELKTLYDGSYQEC-----QRVSGKKYDVN- 120

  Fly   120 GAKYCLSRMQFESLLMEAAGADA------LTLSIGTCIPSSCSAAQLSRWMSGHLKDMFGQNSTE 178
               ||...:.....:...|.:::      |.|.|..|:|.||:...:.        |:|.:.|..
Worm   121 ---YCYLLLTPGKNVSSCAPSNSKSLYSQLPLRIAVCLPDSCNHQDMI--------DIFNELSPY 174

  Fly   179 ATLVQEKDCS---LAHRDPMNGLDWLAVSILILLCIVVLLATILDY---------SCVSN----K 227
            ........|:   :....|.    |.....||::.::..:|:|:||         |...|    |
Worm   175 PFTACSAYCTKNEVKKDTPF----WGFSIFLIVMVVIAAIASIVDYVRETVYGLSSQKENNTFFK 235

  Fly   228 LLSSFSLRKNVPQLLKTSNTPSPRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVAWAQ 292
            :|.:|||..|...||......| ..|..|:.||.|::.|::.||.::||:||.|:.  .::.:..
Worm   236 ILLTFSLWTNAELLLSVKEQKS-GFIKSLDCIRLLSMCWVVTGHSFLYLILADTLE--PVLDFPT 297

  Fly   293 MPFSMILQSGTTSVDTFFLLSGLLLVLSALREMDRSKGRLHVP----LMYLHRLVRLTPVLALAV 353
            ..::.:|.:...||||||:||| ::|.....:...:|..:..|    |.|:||.:||||.:.|.:
Worm   298 YFWNHLLLNAFVSVDTFFVLSG-IVVAYLFFKTKLTKKTITSPMTWILFYVHRYLRLTPPVMLFI 361

  Fly   354 LIFMTLFPRLD---SGPLWNQFTSSSELCSDTWWATLLYVQNY---AAPGRMCLGHSWYLAVDMQ 412
            ..|....|.:.   |....||....:..|...||..|||:.|:   .:....|.|.:||||||.|
Worm   362 GFFTVYTPYIQGAFSASELNQMAPQAAACKTLWWQNLLYINNFDDGNSQNSTCYGITWYLAVDTQ 426

  Fly   413 LYIISPLLLIALYKWGKKAIAGIVLLILLLSGCVFGIVMLRDL-KVF----DRYGNLGGDSTE-M 471
            ||:::|::|:|||   ....||..:::   :|||..|:....| .|:    |..||  ||.|: .
Worm   427 LYLVAPIVLVALY---FSFAAGTAIIV---AGCVGSIITTYILFGVYNVPADIIGN--GDQTKFF 483

  Fly   472 RLIYYTTHARATPWLIGLLFGYFLHHQNVRKTRLPKWLALVLWILSLSMLATVIFAVYPYTQSGA 536
            .:.|.....|..|:|:|||.||.|.....||.||...||:..||.:..:....:||.|.| ..||
Worm   484 NIAYSKPWIRCPPYLVGLLTGYLLATYGSRKIRLNWALAIAGWITAFVIAGFCLFATYDY-DKGA 547

  Fly   537 GDISAMAGAFYLCCSRIAWPLALCWIIWACQNGLAPIVNEFLSWSFWQPLSKLSYCLYIWHLLVE 601
             ..|....|.:....|:.|.:.:||::.|...|....:::|:|...|||..:||||.||.|.:|
Worm   548 -HWSTFTRATFYNFHRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMV- 610

  Fly   602 TVHIARIKTSLHFSDYDAILRFWSDF-------GITLFVSMFMHLCV-EVPLGRLEMELLKR 655
            ..:...:...||:|.      .|..|       .:..:|..|...|: |||:.:||..|:::
Worm   611 LYYYLNVGGVLHYSS------AWQVFTYIAIPATLLSYVLAFFWSCLFEVPILKLEKMLIEK 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42329	NP_608590.2	NRF	71..179	CDD:214781	29/121 (24%)
		OafA	253..648	CDD:224748	133/418 (32%)
		Acyl_transf_3	253..639	CDD:280013	129/408 (32%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	27/124 (22%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	134/425 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730