DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42329 and oac-20

DIOPT Version :9

Sequence 1:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_507007.3	Gene:	oac-20 / 185375	WormBaseID:	WBGene00009488	Length:	719	Species:	Caenorhabditis elegans

Alignment Length:	721	Identity:	199/721 - (27%)
Similarity:	314/721 - (43%)	Gaps:	105/721 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LTTAQTYSSKDLLTWMQSSNFGYQVLQQALNDNQSSSAAEASCLAEVRLLLTGAEAKSLPALRVF 78
            ||......:.|..||:.|.:...:|..:.:...:.|...|        |||    ..:..||...
Worm    35 LTGVNPQCNNDTETWLHSLDILTEVSLECILSKKCSKKEE--------LLL----RDNFYALEQL 87

  Fly    79 DAWGKFPQ-GLLYGHFMDMGNYESCLSLDLSKSLGNVMTINAGAKYC---LSRMQFESLLMEAAG 139
            |::||||. ||.....:..|:|:.|..:. .||.....|     .||   |...:..|...|...
Worm    88 DSFGKFPSIGLFEVPLIFDGSYQECERIS-GKSETKYET-----NYCYVLLIPGKNSSHCHETKS 146

  Fly   140 AD----ALTLSIGTCIPSSCSAAQLSRWMSGHLKDMFGQNSTEATLVQEKDCSLAHRDPMNGLDW 200
            .|    .|......|:|:||:..::|        |:..:.|..........|| ::....|...|
Worm   147 GDLSPTTLFFRSAVCMPNSCNQREIS--------DIINEISDIPFTACGSQCS-SYPVEKNSAFW 202

  Fly   201 LAVSILILLCIVVLLATILDY--SCVSN--------------KLLSSFSLRKNVPQLLKTSNTPS 249
            .....:|::..:.:|||.:||  ..::.              |:|.||||..|. :|:.:.....
Worm   203 GFSVFMIVMISIAILATSVDYILDAIATDEEQREKNKRHLLLKILISFSLWTNA-ELILSVKEQK 266

  Fly   250 PRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVAWAQMPFSMILQSGTTSVDTFFLLSG 314
            ...|.||:.||.|:::|::.||....::....:  ..:..:.:..::.:|.:...||||||||||
Worm   267 VGFIKCLDCIRFLSMLWVVSGHTVSNIMFPDVL--LPVTTFTKHFWNHLLLNAFVSVDTFFLLSG 329

  Fly   315 LLLVLSALREMDRSK-GRLHVP----LMYLHRLVRLTPVLALAVLIFMTLFPRLDSGPL----WN 370
              :|:|.|...:|.| .::..|    |.|:||.:||||.. :..|.|..::.....||.    .|
Worm   330 --IVVSYLFFKNRMKSSQIKSPLTWILFYVHRYLRLTPPY-MIFLGFYIVYSEYVQGPTAAAGLN 391

  Fly   371 QFTSSSELCSDTWWATLLYVQNYAAPGRMCLGHSWYLAVDMQLYIISPLLLIAL---YKWGKKAI 432
            ....|.|.|..|||..|||:.|:......|...:||||||.|||:|:|::||||   :.||..|:
Worm   392 AAIYSVESCKKTWWRNLLYINNFGDSTHACYAITWYLAVDTQLYLIAPIVLIALWFSFVWGALAV 456

  Fly   433 AGIVLLILLLSGCVFGIVMLRDLKV-----FDRYGNLGGDSTEM-RLIYYTTHARATPWLIGLLF 491
            |         :||...||.:..|..     .|::|.  |...:. :::|.....|.||:|||||.
Worm   457 A---------AGCAGSIVTVYVLYAEYHLPADQFGK--GSLLDFGKILYQKPWVRCTPYLIGLLV 510

  Fly   492 GYFLHHQNVRKTRLPKWLALVLWILSLSMLATVIFAVYPYTQSGAGDISAMAGAFYLCCSRIAWP 556
            ||.|.....|:.||...||:|.|:::..:....:|:...|.:....  |....|.|...||..|.
Worm   511 GYGLAVFGKRRVRLHWALAVVGWLIAFGIAVACLFSTNDYDKGAVW--SDFEKATYYNFSRFFWA 573

  Fly   557 LALCWIIWACQNGLAPIVNEFLSWSFWQPLSKLSYCLYIWHLLVETVHIARIKTSLHFSDYDAIL 621
            :|:.|:|.|...|....:|.|:|...|||..|||||.||.|..:.:.:....:..:|   |.:..
Worm   574 IAVSWVIVANHMGWGGPINNFMSHPIWQPFGKLSYCAYIVHFFLISWYTNISEAPMH---YYSTF 635

  Fly   622 RFWSDFGITL----FVSMFMHLCV-EVPLGRLEMELLK--------RCQKKEDSPESPRVDPSTE 673
            :.|..:.:.:    ::..|...|: |:|..:||..|::        |...|....|.| |:|...
Worm   636 QVWIYYAVPVTIIAYIFAFFWSCLFEIPTLKLEKMLIEAILGAGHTRASGKVGELEKP-VEPRIG 699

  Fly   674 PTEVIP 679
            ..:::|
Worm   700 SWDIVP 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42329	NP_608590.2	NRF	71..179	CDD:214781	29/115 (25%)
		OafA	253..648	CDD:224748	130/417 (31%)
		Acyl_transf_3	253..639	CDD:280013	127/407 (31%)
oac-20	NP_507007.3	NRF	80..192	CDD:214781	31/126 (25%)
oac-20	NP_507007.3	Acyl_transf_3	270..654	CDD:376607	126/404 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730