DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42329 and oac-3

DIOPT Version :9

Sequence 1:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	696	Identity:	199/696 - (28%)
Similarity:	310/696 - (44%)	Gaps:	114/696 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SKDLLTWMQSSNFGYQVLQQALNDNQSSSAAEASCL------AEVRLLLTGAEAKSLPALRVFDA 80
            :||:.||:.|.              :..:||.:.||      |.:..:|    ..::.|::.:||
Worm    48 TKDMKTWISSI--------------EQFTAASSDCLFFKNCTASILNIL----KDNIYAIQQYDA 94

  Fly    81 WGKFPQ-GLLYGHFMDMGNYESCLSLDLSKSLGNVMTINAGAKYCLSRMQFESLLMEAAGADALT 144
            :.|.|. |||....:..|:|:.|         ..:..:.....||.      .||:....|:...
Worm    95 FAKIPSAGLLEVSLVFDGSYQEC---------HRISGVKYETNYCY------VLLVPGRNANCSG 144

  Fly   145 LSI---GT--------CIPSSCSAAQLSRWMSGHLKDMFGQNSTE-----ATLVQEKDCSLAHRD 193
            .||   ||        |:|.||:        |....|::.|.|..     ||...::|.
Worm   145 GSIQNAGTSVAFRRAVCMPKSCA--------SSDTVDLYNQLSALPLTACATFCSQRDV------ 195

  Fly   194 PMNGLDWLAVSILILLCIVVLLATILDY---------------SCVSNKLLSSFSLRKNVPQLLK 243
            |.:...|...:.:.::...|:|||.:||               |....:||.|||...|...:|.
Worm   196 PKDSAFWGFSAFMFVIVSTVILATTVDYLRESVYDISSKSIEKSASLYRLLYSFSFWTNASTILN 260

  Fly   244 TSNTPSPRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVAWAQMPFSMILQSGTTSVDT 308
            .|:.|:.. |.||:.||.|::.|::.||...|...|.|:  ..|.::|.........:...||||
Worm   261 VSSQPATH-IKCLDCIRGLSMAWVLSGHMLNYFAFADTL--MPIKSFANYFADYFFMNAVFSVDT 322

  Fly   309 FFLLSGLLLVLSALREMDRSKGRLHVP----LMYLHRLVRLTPVLALAVLIFMTLFPRLDSGP-- 367
            |||:||:.:..|..|....:| .|..|    |.|:||.|||||.. :..:.|..::.....||
Worm   323 FFLVSGITVAYSFFRLKPTTK-TLKSPATWILFYVHRYVRLTPPY-IIFIGFYAVYALYIQGPLA 385

  Fly   368 --LWNQFTSSSELCSDTWWATLLYVQNYAAPGRMCLGHSWYLAVDMQLYIISPLLLIALYKWGKK 430
              |:|......|.|..:||..|:|:.|:......|.|.|||||||.|||:::|:||:|| .|  .
Worm   386 ASLFNFTVLQVEACKASWWRNLIYINNFDNGENPCYGPSWYLAVDTQLYLVAPILLVAL-TW--T 447

  Fly   431 AIAGIVLLILLLSGCVFGIVMLRDL-KVFDR-YGNLGGDSTEM--RLIYYTTHARATPWLIGLLF 491
            .|||:|:.::   ||:..::::..| :.||. ..:...||:..  ..:|.....|..|:|:|:|.
Worm   448 PIAGLVVSMV---GCIGSMIIVFILYQKFDMPADSFNADSSGKFNFYVYQKPWTRCPPYLVGILG 509

  Fly   492 GYFLHHQNVRKTRLPKWLALVLWILSLSMLATVIFAVYPYTQSGAGD-ISAMAGAFYLCCSRIAW 555
            ||||........:|.....|:..:|::.::...:.|...|.|   || .|:...|.|...||..|
Worm   510 GYFLSRFATSPVKLSFVKKLIPMLLAVGLIFACLTANIGYDQ---GDHWSSWTKATYYNFSRFFW 571

  Fly   556 PLALCWIIWACQNGLAPIVNEFLSWSFWQPLSKLSYCLYIWHLLVETVHIARIKTSLHF-SDYDA 619
            .|::.|||.:|..|.|..:..|:|...||||.:|||..||.||:|....:......||| |.:..
Worm   572 ALSVLWIILSCHYGWAGPIGNFMSHPIWQPLGRLSYSAYIVHLMVVYYFLNVGDKPLHFVSTWQV 636

  Fly   620 ILRFWSDFGITLFVSMFMHLCV-EVPLGRLEMELLKRCQKKEDSPE 664
            .:.:.....|..::..|...|: |:|:.:||..||:...:|:..||
Worm   637 YVYYILPATILTYIFAFFWSCLFEIPVVKLEKFLLEILLRKKRLPE 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42329	NP_608590.2	NRF	71..179	CDD:214781	28/124 (23%)
		OafA	253..648	CDD:224748	132/409 (32%)
		Acyl_transf_3	253..639	CDD:280013	129/399 (32%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	30/128 (23%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	128/396 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730