DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42329 and oac-14

DIOPT Version :9

Sequence 1:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_509701.1	Gene:	oac-14 / 181226	WormBaseID:	WBGene00008602	Length:	710	Species:	Caenorhabditis elegans

Alignment Length:	737	Identity:	200/737 - (27%)
Similarity:	331/737 - (44%)	Gaps:	120/737 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIVALIGIMGVGVLTTAQTYSSKDLLTWMQSSNFGYQVLQQALNDNQS--------SSAAEA--- 54
            :::.|:...|...|.....:..|.|          :.:..|.|||.|:        :..:||
Worm     7 VVLLLLSTSGAVTLDWKDIFKPKPL----------HGLSPQCLNDTQTWIKSLELFAGVSEACLK 61

  Fly    55 --SC-LAEVRLLLTGAEAKSLPALRVFDAWGKFP-QGLLYGHFMDMGNYESCLSLDLSKSLGNVM 115
              :| |.|:::|     ..:|.|::..|::||.| .|:|....:..|:|:.|         ..|.
Worm    62 KQTCSLKELKIL-----KANLYAIQELDSFGKLPVPGMLEVATLYDGSYQEC---------KRVS 112

  Fly   116 TINAGAKYC-LSRMQFESLLMEAAGADA----LTLSIGTCIPSSCSAAQLSRWMSGHLKDMFGQN 175
            .:.....|| |.....::....|:|:.:    |.:.:..|:|.||:..::.        |:|.|.
Worm   113 GVKYNTNYCYLMLKPGKNASCSASGSSSAYSMLPMRLAVCLPDSCNQHEII--------DIFNQL 169

  Fly   176 STEATLVQEKDCS---LAHRDPMNGLDWLAVSILILLCIVVLLATILDY-------------SCV 224
            |..........||   :....|.    |.....||::.::.|.|::.||             ..|
Worm   170 SPYPFTACHAYCSEYEVKKDTPF----WGFSIFLIVMVVIALAASLTDYIRDTVYGIKSIKERNV 230

  Fly   225 SNKLLSSFSLRKNVPQLLKTSNTPSPRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVA 289
            ..|:|.||||..|. :||.:.....|..|..|:.||..::.|::.||.::||:|:.|.  ..::.
Worm   231 FLKILLSFSLWTNA-ELLLSVKEQKPGFIKSLDCIRLFSMCWVVTGHSFIYLVLSDTF--MPVID 292

  Fly   290 WAQMPFSMILQSGTTSVDTFFLLSGLLLVLSALREMDRSKGRLHVP----LMYLHRLVRLTPVLA 350
            :.:..::.:|.:...||||||:||||:|.....:...:.|..:: |    :.|:||.:||||.:.
Worm   293 FPKHFWNHLLLNAFVSVDTFFVLSGLVLTYMFFKTTPKKKMIVN-PVTWIMFYVHRYLRLTPPIM 356

  Fly   351 LAVLIFMTLFPRLDSGPL----WNQFTSSSELCSDTWWATLLYVQNYAAPGRM-CLGHSWYLAVD 410
            |.:..|....|.: .||.    .||....::.|..|||..|||:.::|:...| |.|.:||||||
Worm   357 LFIGFFTVYAPYI-QGPFSASQMNQLVMEADECKTTWWQNLLYINDFASSNSMGCYGPTWYLAVD 420

  Fly   411 MQLYIISPLLLIALYKWGKKAIAGIVLLILLLSGCVFGIVMLRDL-KVF----DRYGNLGGDSTE 470
            .|||:::|::||.||      .:..|...|:::|||..|:....| .|:    |.:|| |..:..
Worm   421 TQLYLVAPIVLIGLY------FSFAVGTGLIVAGCVGSIITTYILFSVYNLPADMFGN-GSGTNF 478

  Fly   471 MRLIYYTTHARATPWLIGLLFGYFLHHQNVRKTRLPKWLALVLWILSLSMLATVIFAVYPYTQSG 535
            ..:.|.....|..|:|:|:|.||.|.....||.||...|:|..||:::.:....:||.|.|.:..
Worm   479 FTIAYEKPWVRCPPYLVGMLTGYLLAVYGNRKIRLNWVLSLAGWIIAVVIAGFCLFATYDYDKGS 543

  Fly   536 AGDISAMAGAFYLCCSRIAWPLALCWIIWACQNGLAPIVNEFLSWSFWQPLSKLSYCLYIWHLLV 600
            ...:.. .|.|| ...|:.|.:.:||::.|...|....:::|:|...|||..:||||.||.|.:|
Worm   544 HWSVFT-RGTFY-NFHRLGWGMFICWVVAANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWVV 606

  Fly   601 ------ETVHIARIKTSLHFSDYDAI-LRFWSDFGITLFVSMFMHLCV-EVPLGRLEMELLK--- 654
                  ...|.....::|....|.:| ..|.|      ::..|...|: |:|..:||..|::
Worm   607 LFWFLNVGGHATHYYSALEVFTYTSIPATFLS------YIFAFFWSCLFEIPTLKLEKMLIEAIL 665

  Fly   655 ---RCQKKEDSPESPRVDPSTE 673
               |...|.:..|:.:..|..|
Worm   666 GTGRPSNKVEPIETGKTTPILE 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42329	NP_608590.2	NRF	71..179	CDD:214781	26/113 (23%)
		OafA	253..648	CDD:224748	129/416 (31%)
		Acyl_transf_3	253..639	CDD:280013	126/406 (31%)
oac-14	NP_509701.1	NRF	76..183	CDD:214781	27/123 (22%)
oac-14	NP_509701.1	OafA	252..656	CDD:224748	130/422 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730