DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42329 and oac-39

DIOPT Version :9

Sequence 1:	NP_608590.2	Gene:	CG42329 / 33312	FlyBaseID:	FBgn0259229	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	757	Identity:	192/757 - (25%)
Similarity:	327/757 - (43%)	Gaps:	147/757 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VLTTAQTYSSKDLLTWMQSSNF----------------GYQVLQQALNDNQSSSAAEASCLAEVR 61
            |:...:.|.:.||:..:...:|                ||.::..|.:....::||.::
Worm    42 VMEQLEKYKTSDLIAALGIHSFSKYTISEECHEELAFLGYGMIDVARHVKHQTTAAPST------ 100

  Fly    62 LLLTGAEAKSLPALRVFDAWGKFPQGLLYGHFMDMGNYESCLSLDL-SKSLGNVMTINAGAKYCL 125
              :|..| |:...:.:.||.||...|:..||.:..|.:..|.|:.: |.||...:   .|..|
Worm   101 --MTDVE-KTRYLIPMMDAAGKIGSGIARGHILSAGAFTECKSVSMHSTSLNRTI---RGDYY-- 157

  Fly   126 SRMQFESLLMEAAGADALTL---SIGTCIPSSCSAAQLSRWMSGHLKDMFGQNSTEATLVQEKDC 187
             |:.|:..:...:..|:..|   .:..|:|.||....|:        |.| :.:..||......|
Worm   158 -RILFDIKMRPNSFNDSCQLPQIGVDICLPWSCRNEDLT--------DYF-REALGATKELSPVC 212

  Fly   188 SLAHRDPMNGL-------DWLAVSILILLCIVVLLATILDY-----------------SCVSNKL 228
            |:.:   :||.       .::.|::::.:....:::..:||                 |.|..|:
Worm   213 SVRN---VNGRTPGFTFGTYVVVTLILSIIATSIVSCTVDYYFQNRRSKIDYERMEGSSNVGWKI 274

  Fly   229 LSSFSLRKNVPQLLKTSNTPSPRVIPCLNGIRCLTIIWIILGHGYMYLLLAPTINAYDIVAWAQM 293
            ..:|||.:||.::.|.........:..||.||.::.:|:||||....|:|..| |..|::.:.:.
Worm   275 FMAFSLYRNVKEIFKMKQCNKEGQVTSLNCIRTISTVWVILGHCAAMLILICT-NPVDLLDFTKT 338

  Fly   294 PFSMILQSGTTSVDTFFLLSGLLLVLSALREMDRSKGRLHVP----LMYLHRLVRLTPVLALAVL 354
            ....:|.:...:|||||.:|..||.....:::.:.:..|..|    :.|:||:.||:|...:|:|
Worm   339 YMGALLVNAYFAVDTFFFISAFLLSFLWFKQLQKQRKALISPGGWMMFYVHRIARLSPAYYIAIL 403

  Fly   355 IFMTLFPR-LDSGPLWNQFTSSSELCSDTWWATLLYVQNYAAPGRMCLGHSWYLAVDMQLYIISP 418
            ....::.| |...|.:.......:.|...:|..|||::|......:|...|||||.|:|||::||
Worm   404 FVTFVYIRMLRDMPAFMSPAIQDDTCQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSP 468

  Fly   419 LLLIALYKWGKKAIAGIVLLILLLSGCVFGIVMLRDLKVFDRYG-----------NLGG-----D 467
            :||::.      ||.|.|.      |....:|.|.....|:.|.           .||.     :
Worm   469 ILLLSF------AIGGAVF------GLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYN 521

  Fly   468 STEMRL---IYYTTHARATPWLIGLLFGYFLHHQNVRKTRLPKWLALVLWILSLSMLATVIFAVY 529
            ..|.|.   .||....|...:::||:.|||:  :.|.|..:..|:..::|:|||..:..|:..:.
Worm   522 ENERRYDVWNYYNPLIRCQIYIMGLVLGYFM--RKVPKININPWVDRIMWVLSLGSMVFVVLVIQ 584

  Fly   530 PYTQSGAGDISAMAGAFYLCCSRIAWPLALCWIIWAC--QNGLAPIVNEFLSWSFWQPLSKLSYC 592
            .|: ||.| .:.:..|.|.|.||:.|..|:.||:.:.  :.||   :.:|:|.|||.||::||:|
Worm   585 DYS-SGDG-WTPVQTALYSCFSRVLWGFAMSWIVISTYYRKGL---IRDFMSLSFWTPLARLSFC 644

  Fly   593 LYIWHLLVETVHIARIKTSLHFSDYD---------------AILRFWSDFGITLFVSMFMHLCVE 642
            .|:.|.:|......|..:.|:||...               .|..|||        |||     |
Worm   645 AYLVHWMVLGYFFGRNHSELYFSTLSYFFLDTVIPVTALSFVIAIFWS--------SMF-----E 696

  Fly   643 VPLGRLEMELLKRCQKKEDSPESPRVDPSTEPTEVIPATSIS 684
            :|..::|..||.|....:.:...|:|  ...|.|:..|..::
Worm   697 IPFAKIEGLLLGRSGTPKANGNLPKV--MIIPLEIPKAGEVN 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42329	NP_608590.2	NRF	71..179	CDD:214781	26/111 (23%)
		OafA	253..648	CDD:224748	126/435 (29%)
		Acyl_transf_3	253..639	CDD:280013	124/426 (29%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	30/126 (24%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	117/407 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.680