Protein Alignment CG5001 and SIS1

DIOPT Version :9

• Sequence 1: NP_001245832.1
• Gene: CG5001 / 33308
• FlyBaseID: FBgn0031322
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_014391.1
• Gene: SIS1 / 855725
• SGDID: S000004952
• Length: 352
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 127/365 - (34%)
• Similarity: 195/365 - (53%)
• Gaps: 44/365 - (12%)

  Fly     6 YKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKYGED 70
            |.:||:..:|.:.|:||.|||.||:||||  |.....:||||::||:|:|:|..|||:||:||.:
Yeast     8 YDLLGVSPSANEQELKKGYRKAALKYHPD--KPTGDTEKFKEISEAFEILNDPQKREIYDQYGLE 70

  Fly    71 GLKSGGTR--NGGPSSNSFTYQFHG--------------DPRATFAQFFGNSNPFASFFDMGDNL 119
            ..:|||..  .|||........|.|              |....|:||||.|:||....|.|
Yeast    71 AARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSG--- 132

  Fly   120 FDKKVFDLDTEPDFFSSPF----GGIGSRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDL 180
                 |...:.|....:..    ||:|..||...|....|||.|.:...|      ::..|:.:|
Yeast   133 -----FSFSSYPSGGGAGMGGMPGGMGGMHGGMGGMPGGFRSASSSPTYP------EEETVQVNL 186

  Fly   181 YVTLEEIYHGCVKKMKISRRIVQADGSSRKEEKFLAISIKPGWKSGTKVTFQKEGDQAP--GKIP 243
            .|:||:::.|..|..||.|:  ...|:|.|.:  :.|.:|||||:|||:|::.:||..|  |: .
Yeast   187 PVSLEDLFVGKKKSFKIGRK--GPHGASEKTQ--IDIQLKPGWKAGTKITYKNQGDYNPQTGR-R 246

  Fly   244 ADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKR 308
            ..:.|:|::|.|..|||:|.||.||..|:.|::|.|....:.|:.|..|.:|.:|. ::|:....
Yeast   247 KTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQP-VQPSQTST 310

  Fly   309 IQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKD 348
            ..|.|:|.||:.:::|:|:|.:.:.:|..|..|||..:.:
Yeast   311 YPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDE 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	127/362 (35%)
		DnaJ	4..65	CDD:278647	29/58 (50%)
		DnaJ_C	174..338	CDD:199909	58/165 (35%)
SIS1	NP_014391.1	DnaJ	2..350	CDD:223560	127/363 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344995
Domainoid	1	1.000	107	1.000	Domainoid score	I1436
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I853
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		otm46486
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	1	1.100	-	-	LDO	PTHR24078
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
TreeFam	0	0.000	Not matched by this tool.
	11	10.820