DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5001 and Dnajb4

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001343292.1	Gene:	Dnajb4 / 67035	MGIID:	1914285	Length:	337	Species:	Mus musculus

Alignment Length:	358	Identity:	189/358 - (52%)
Similarity:	246/358 - (68%)	Gaps:	32/358 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYD 65
            ||||||.|||:.|.|||:::||||||.||::||||||:..||:||||||||||||||..|||:||
Mouse     1 MGKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYD 65

  Fly    66 KYGEDGLK--SGGTRNGGPSSNSFTYQFHGDPRATFAQFFGNSNPFASFFD--MGDNLFDKKVFD 126
            ::||:|||  :|||...|   .:|.|.|||||.||||.|||.||||..||.  ||... |.:..:
Mouse    66 QFGEEGLKGGAGGTDGQG---GTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGR-DSEEME 126

  Fly   127 LDTEPDFFSSPFGGIG---SRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDLYVTLEEIY 188
            :|.:| |.:..|...|   .|:.:|    ||              ..|||||:.|:|.|:|||||
Mouse   127 IDGDP-FSAFGFSMNGYPRDRNSVG----PS--------------RLKQDPPIIHELKVSLEEIY 172

  Fly   189 HGCVKKMKISRRIVQADGSS-RKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGKIPADIVFIIRD 252
            .||.|:|||||:.:..||.| |.|:|.|.|.||.|||.|||:||.:|||:.|..|||||||:|:|
Mouse   173 SGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFVIKD 237

  Fly   253 KPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKRIQGYGLPFP 317
            |.|..|||:||::.|||:::|::||||....||||.|..|.:| :.:|:||...:|:.|||||||
Mouse   238 KEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMS-VTDIVKPGMRRRVIGYGLPFP 301

  Fly   318 KDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML 350
            |:..::||||:.||:.||:.::||.||:|:..|
Mouse   302 KNPDQRGDLLIEFDVSFPDVISAASKEILRKHL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	187/353 (53%)
		DnaJ	4..65	CDD:278647	43/60 (72%)
		DnaJ_C	174..338	CDD:199909	91/164 (55%)
Dnajb4	NP_001343292.1	DnaJ	1..332	CDD:223560	188/354 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3258
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2098
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8681
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.760