DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5001 and dnajb2

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001073462.1	Gene:	dnajb2 / 561686	ZFINID:	ZDB-GENE-061013-537	Length:	389	Species:	Danio rerio

Alignment Length:	234	Identity:	88/234 - (37%)
Similarity:	121/234 - (51%)	Gaps:	37/234 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DYYKILGLPKTATDDEIKKAYRKLALRYHPDKN--KAANAEDKFKEVAEAYEVLSDKSKREVYDK 66
            |||.:||:.::|:.|:||||||||||::|||||  ....||.||||:|||||||||||||:.||:
Zfish     3 DYYDVLGVSRSASPDDIKKAYRKLALQWHPDKNPDNKEEAEKKFKEIAEAYEVLSDKSKRDDYDR 67

  Fly    67 YGEDGLKSGGTRNGGPSSN---SFTYQFHGDPRATFAQFFGNSNPFASFFD------------MG 116
            ||...:.|.|:.:.|...:   .||:.|. .|...|.:|||..:|||.|||            ..
Zfish    68 YGRSDMPSSGSGSSGSFPDDFPGFTFTFR-SPDEVFREFFGGQDPFADFFDDFPFGGMHSGFHSS 131

  Fly   117 DNLFDKKVFDL-DTEPDF--FSSPFGGIGSRHGLGSGFRPSFRSHSFNVH--------TPFKKEQ 170
            ..|...:.|.. ....||  |||..||:||..|      .:|:|.|.:..        |...:|.
Zfish   132 SRLGPSRFFSFPSANADFTSFSSSLGGMGSMGG------ANFKSVSTSTRVVNGKRLTTKKVREN 190

  Fly   171 KQD-PPVEHDLYVTLEEIYHGCVKKMKISRRIVQADGSS 208
            .|: ..||.| .|....:.:|...:|.::..:.:.:.||
Zfish   191 GQERTEVEED-GVLKSVLINGVEDEMALALELSRREQSS 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	88/234 (38%)
		DnaJ	4..65	CDD:278647	41/62 (66%)
		DnaJ_C	174..338	CDD:199909	8/35 (23%)
dnajb2	NP_001073462.1	DnaJ	2..>108	CDD:223560	55/105 (52%)
		DnaJ	3..66	CDD:278647	41/62 (66%)
		UIM	269..285	CDD:280900
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740