DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5001 and DNAJB12

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001352009.1	Gene:	DNAJB12 / 54788	HGNCID:	14891	Length:	377	Species:	Homo sapiens

Alignment Length:	173	Identity:	63/173 - (36%)
Similarity:	87/173 - (50%)	Gaps:	49/173 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKY 67
            ||||:|||:.:.|:|:::|||||:|||::|||||.|..|.:.||.:..||.|||:..||:.||::
Human   109 KDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQF 173

  Fly    68 GEDGLKSGGTRNGGPSSNSFTYQFHGDPRATFAQFFGNSNPFASFFDMGDNLFDKKVFDLDTEP- 131
            |:|  ||...|:|         ..|||                  |..|        |:.|..|
Human   174 GDD--KSQAARHG---------HGHGD------------------FHRG--------FEADISPE 201

  Fly   132 DFFSSPFGGIGSRHGLGSGFRPSFRSHSF-NVHTPFKKEQKQD 173
            |.|:..|||         || ||...|.: |....:..:|:||
Human   202 DLFNMFFGG---------GF-PSSNVHVYSNGRMRYTYQQRQD 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	63/173 (36%)
		DnaJ	4..65	CDD:278647	32/60 (53%)
		DnaJ_C	174..338	CDD:199909	63/173 (36%)
DNAJB12	NP_001352009.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..92
		DnaJ	110..>236	CDD:333066	62/172 (36%)
		DUF1977	268..368	CDD:312722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740