DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5001 and Dnajb5

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_038966057.1	Gene:	Dnajb5 / 313811	RGDID:	1307453	Length:	420	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	191/361 - (52%)
Similarity:	248/361 - (68%)	Gaps:	27/361 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYD 65
            ||||||||||:|..|.:|||||||||:||:|||||||..|||:||||:||||:||||..||.:||
  Rat    73 MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYD 137

  Fly    66 KYGEDGLKSGGTRNGGPSSNSFTYQFHGDPRATFAQFFGNSNPFASFFDMGDNL-----FDKKVF 125
            :|||:|||:||..:|| |..||.|.|||||.||||.|||.||||..||....:.     ||....
  Rat   138 QYGEEGLKTGGGTSGG-SGGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSGFDPDDM 201

  Fly   126 DLDTEPDFFSSPFGGIG--SRHGLGSGFRPSFRSHSFNVHTP---FKKEQKQDPPVEHDLYVTLE 185
            |:|.:.|    |||..|  ..:||..|.|          ..|   :.:.:.|||||.|:|.|:||
  Rat   202 DVDEDED----PFGAFGRFGFNGLSRGPR----------RAPEPLYPRRKVQDPPVVHELRVSLE 252

  Fly   186 EIYHGCVKKMKISRRIVQADGSS-RKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGKIPADIVFI 249
            |||||..|:|||:||.:..||.: |.|:|.|.|.||.|||.|||:||.||||..|..|||||||:
  Rat   253 EIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFV 317

  Fly   250 IRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKRIQGYGL 314
            ::|||||.|:|:|:::.|:|.::||:||||....:||:.|..:.: ...::|||.||||::|.||
  Rat   318 LKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPL-PCNDVIKPGTVKRLRGEGL 381

  Fly   315 PFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML 350
            ||||..|::|||:|.|.::||::||...:::||..|
  Rat   382 PFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	188/356 (53%)
		DnaJ	4..65	CDD:278647	44/60 (73%)
		DnaJ_C	174..338	CDD:199909	89/164 (54%)
Dnajb5	XP_038966057.1	DnaJ	72..415	CDD:223560	189/357 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347708
Domainoid	1	1.000	190	1.000	Domainoid score	I3167
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8176
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2057
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8916
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	1	1.100	-	-	LDO	PTHR24078
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810