DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5001 and DNAJC16

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_056106.1	Gene:	DNAJC16 / 23341	HGNCID:	29157	Length:	782	Species:	Homo sapiens

Alignment Length:	364	Identity:	93/364 - (25%)
Similarity:	146/364 - (40%)	Gaps:	104/364 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKYG 68
            |.|::||:.:||:..:|||||:|||..:||||||...|||||.::::|||:||::.||..||:||
Human    29 DPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYG 93

  Fly    69 EDGLKSGGTRNGGPSSNSFTYQFHGDPRA-TFAQFFGNSNPFASFF------DMGDNLFDKKVFD 126
            :.|...|             ||.....|. .|..|..|.....|||      :..|::.:|.:..
Human    94 DAGENQG-------------YQKQQQQREYRFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLH 145

  Fly   127 L-----DTEPDFFSSPF------------------------------GGIGSRHGLGSGFRPSFR 156
            .     :..||.|..|:                              .|||..|   :|:....
Human   146 FSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVH---AGYERRL- 206

  Fly   157 SHSFNVH-TPF-------KKEQKQDPPVEHDLYVTLEEIYHG-CVKKMKISRRIVQADGSSRKEE 212
            :|....| ||.       |.....:..|..:|...:|.:..| .|:|:           :::...
Human   207 AHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKV-----------TNKNYV 260

  Fly   213 KFLAISIKPGWKSGTK---VTFQKEGDQAP-----GKIPADIVFIIRDKPHAMFKREGSDLRYTA 269
            :||:     ||:...|   :.|    ||.|     .|:.|   |..:|  :..|......||.|.
Human   261 RFLS-----GWQQENKPHVLLF----DQTPIVPLLYKLTA---FAYKD--YLSFGYVYVGLRGTE 311

  Fly   270 RLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKR 308
            .:|.:.   .:....||:...|..|:...::|:...:|:
Human   312 EMTRRY---NINIYAPTLLVFKEHINRPADVIQARGMKK 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	93/364 (26%)
		DnaJ	4..65	CDD:278647	32/60 (53%)
		DnaJ_C	174..338	CDD:199909	30/144 (21%)
DNAJC16	NP_056106.1	DnaJ	29..>142	CDD:333066	48/125 (38%)
		TRX_DnaJ	136..245	CDD:239261	19/112 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	562..593
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910