DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5001 and dnj-10

DIOPT Version :9

Sequence 1:	NP_001245832.1	Gene:	CG5001 / 33308	FlyBaseID:	FBgn0031322	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_498902.1	Gene:	dnj-10 / 176211	WormBaseID:	WBGene00001028	Length:	456	Species:	Caenorhabditis elegans

Alignment Length:	388	Identity:	102/388 - (26%)
Similarity:	157/388 - (40%)	Gaps:	94/388 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKY 67
            :||||.||:.|.:....|||||.:||.:||||.||...|:.||:|::||||||||.:||:.||.|
Worm    43 EDYYKTLGVDKKSDAKAIKKAYFQLAKKYHPDVNKTKEAQTKFQEISEAYEVLSDDTKRQEYDAY 107

  Fly    68 GEDGLKSGGTRNGGPSSNSFTYQFHG--DPRATFAQFFGNSNPFASF-FD------MGDNLFDKK 123
            |..|..:||  .||...    :..||  |....|.:.||.......| ||      .|.:...:.
Worm   108 GSGGGPAGG--RGGAGG----FHHHGNVDVNEIFRRAFGGGGGMGGFNFDNFAQSAFGHSAAQEM 166

  Fly   124 VFDLDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFKK---------EQKQDPPVEHD 179
            |.|:..|                  ...|.:.::.|.||.....|         .:|...|..:.
Worm   167 VMDISFE------------------EAVRGATKNVSVNVVEDCLKCHGTQVEPGHKKTSCPYCNG 213

  Fly   180 LYVTLEEIYHGCVKKMKISRRIVQADGSSRK-------------EEKFLAISIKPGWKSGTKVTF 231
            .....:.:..|...:...:|  .:..|...|             :.:.::.::..|..:|..:.|
Worm   214 TGAVSQRLQGGFFYQTTCNR--CRGSGHYNKNPCQECEGEGQTVQRRQVSFNVPAGTNNGDSLKF 276

  Fly   232 QKEGDQAPGKIPADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGD------ 290
            |      .||....:.|.:  .|...|:||..|:.....::|.||:.|...:||.::||
Worm   277 Q------VGKNQLFVRFNV--APSLKFRREKDDIHCDVDISLAQAVLGGTVKVPGINGDTYVHIP 333

  Fly   291 -------KLRISTMQEIIKPNTVKRIQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVL 346
                   |:|::       ...|||:..||         .||..:...:..|:.|||.||:::
Worm   334 AGTGSHTKMRLT-------GKGVKRLHSYG---------NGDQYMHIKVTVPKYLTAEQKQIM 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	102/388 (26%)
		DnaJ	4..65	CDD:278647	34/60 (57%)
		DnaJ_C	174..338	CDD:199909	35/189 (19%)
dnj-10	NP_498902.1	DnaJ	41..387	CDD:223560	102/388 (26%)
		DnaJ	44..105	CDD:278647	34/60 (57%)
		DnaJ_C	165..372	CDD:199909	44/250 (18%)
		DnaJ_zf	191..252	CDD:199908	7/62 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910