DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5126 and CG6830

DIOPT Version :9

Sequence 1:	NP_608584.1	Gene:	CG5126 / 33306	FlyBaseID:	FBgn0031320	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	96/482 - (19%)
Similarity:	164/482 - (34%)	Gaps:	165/482 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QQQQLDYIERHLVYDIFKNFGPSAS------LESHSVECSNGLDGFMSALYTVTLDVVIAERK-R 61
            |.:..|.|...|..|.||....||.      |.|.|...:...|.|.|.|..|.::..:.:.. :
  Fly   475 QPENTDQIPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVK 539

  Fly    62 TEVVLVKFMKGTEEFRESSNSYIQFSN------EIFAYAEILPAYENVL-----------RTSHL 109
            |...::|.        .|.|..|.||:      ||..|:..:||:|...           ::..|
  Fly   540 TFSYILKV--------HSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRL 596

  Fly   110 ESEVVKNWVPCCYFARFGHVEGLGNGRESVLALKHLKGDGYQLGPRLTLRRDQLEAMVGL----- 169
            ..:|.|.:                      |.|::|:..|:::          ::.|:|:
  Fly   597 SKDVSKEY----------------------LLLENLQPSGFKM----------VDRMIGMDLEHS 629

  Fly   170 ------VGPFHALGYATKILQPNVHARLRAGVVDMPFVSSSGKGIFDVLYRVAFDRFYEFYDRQK 228
                  :..:||             |.|:...::.|:......|||.......|...  |.:.:|
  Fly   630 KCTLKKLAQWHA-------------ASLKYKELNGPYSPKYNNGIFTEQTAPIFKGM--FVNTKK 679

  Fly   229 EQL-----LQGADPGFGAAIERLREKYFKQPTLL---LERIRTSSFAEDQPDSHFATFLHGDYNR 285
            ..:     ..|.|           |...|.|.:|   ::||...:...:|.   |....|||...
  Fly   680 SFIEEVSKFDGVD-----------EYLHKMPEILDTYVDRILEDAKINEQA---FNVLNHGDAWI 730

  Fly   286 NNVLFHYGAEDKVDAIKAIDFQELRFSTTAIDLSFFMYMNTPSEGRKEIYADLLRKYHRSMIEML 350
            ||::|.|.::.:|.....:|.|..::...|.||.:|:..:|..:.:.:.:..|:|.||::|.|..
  Fly   731 NNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHA 795

  Fly   351 ELV------------------------------LRRNRNELTDD-RVDQLLQE-----------Y 373
            :|:                              |....|:.||| ..|..|..           :
  Fly   796 KLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREAMF 860

  Fly   374 SFERFNAHFKRYAFYGPMVCMHFLPWL 400
            |.||:.|:.:|           .:||:
  Fly   861 SNERYRANIER-----------VMPWI 876

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5126	NP_608584.1	EcKinase	41..353	CDD:281023	69/348 (20%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	70/352 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010