Protein Alignment CG4896 and Gpatch8

DIOPT Version :10

• Sequence 1: NP_608583.5
• Gene: CG4896 / 33305
• FlyBaseID: FBgn0031319
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: NP_001385812.1
• Gene: Gpatch8 / 685233
• RGDID: 1596463
• Length: 1513
• Species: Rattus norvegicus
• Alignment Length: 1171
• Identity: 208/1171 - (17%)
• Similarity: 350/1171 - (29%)
• Gaps: 433/1171 - (36%)

  Fly    76 YEDQGNYNSRQNLDQRHGEDKYDRRHADSQGRRDHDSNYDKSGQDMDKDR-------DHRW---- 129
            |:..|.......||  :.||..:||......:.|.:....|....:||::       |.|.
  Rat    76 YDVMGMGRMEMELD--YAEDATERRRVLEVEKEDTEELRQKYKDYVDKEKAIAKALEDLRANFYC 138

  Fly   130 ----KNYDRVSRERNH-DDFDRGSERSSRSNDQRQFNNNGNSNSSSSYRDREK---------ERD 180
                |.|.:.....|| :.:|...::..:...||:|..|.:|.|....:.:||         |:.
  Rat   139 ELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQEKALRRLHELAEQR 203

  Fly   181 RDRRCSSDE-----------DSDMASEFRQRGAYNSGSSV---------------EPLNNI---- 215
            :...|:...           |.|...|.:...:.|||:|.               .|..::
  Rat   204 KQAECAPGSGPMFRPTTVAVDEDGGEEDKDESSTNSGASAISSCGFGSDFSTEKGGPFTSVQITN 268

  Fly   216 --------------ILFGLKKH------------------------------------------- 223
                          |.||:|.:
  Rat   269 STGLSQASGLASQGISFGIKNNLGPPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTK 333

  Fly   224 ------------VTEADIMGEL--IKVDLEPTS-----------IRVMRKQQTGA---------- 253
                        |.|.|..|.|  .|.|.:|..           .|:.|::.|||
  Rat   334 AEEKSSDQGVQKVGETDGGGNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGTGATEPEYYHYIP 398

  Fly   254 -SRC-----FAFVEFKTVEEATRWMELTQGVLQLGDHRVTMQYSHTRISDWT----------CIK 302
             :.|     |.|:.|.   .|:..||        ||||     :|::.:...          |.|
  Rat   399 PAHCKVKPNFPFLLFM---RASEQME--------GDHR-----THSKNAPENRKGSSPRPKGCSK 447

  Fly   303 CGASNFKRRFQCYMCNASRAESENALYGAGE--GVDEISQILTKKIMLRGLDALTNEEGVLTALQ 365
            ..||....:   .:.:.|..:.|..:.|..|  |..|     |||....|    ..|:.|.:..:
  Rat   448 AAASQGAEK---TVSDVSEPQKEATVVGPSEPGGKTE-----TKKCSGEG----EGEQSVESLRE 500

  Fly   366 QRLPELAKTVSKVLVSRDALTNASRGICYLNFDTLIDSMNVFNGLTALDPPLTLDDKTVIVTYCI 430
            ....::.::..|.:......|.|.:|              ..:......|.|:.|:.|.:
  Rat   501 SSESQMCESDPKEISQATPATKAGQG--------------PKHPTGPFFPVLSKDESTAL----- 546

  Fly   431 DSENRQMMPAEGNFFRAGETAMSPSAITAAYTLADVPRLAEYSASVYASNPLEHANYVQYYTDYY 495
                  ..|:|...|...|..:|                       |:.|||           |:
  Rat   547 ------QWPSELLIFTKAEPPIS-----------------------YSCNPL-----------YF 571

  Fly   496 TTEISKNCRDRQV--TE-----ANSGAAVALSAIQRKQRKVSQMETTVSVTEAKVAFLARG---- 549
            ..::|:| :|.:.  ||     .:|......|...|:..|..:.|.:|.::|.:|...|.|
  Rat   572 DFKLSRN-KDAKAKGTEKPKDVGDSSKGHLQSPDPREPNKSKEGEQSVVLSEGRVDEPASGAACS 635

  Fly   550 ---ESAPKGNDGKKYDTPDVSKYQYDETSGYYYDHVTGLYYDAHSQYYYNNETGAYLYWDQKRST 611
               :..|.|:...:.:....|.....|.||..:.|.....:...|::              ||
  Rat   636 SLTKQEPGGSHASETEDTGRSHPNKKEPSGKSHRHKKKKKHKKSSKH--------------KR-- 684

  Fly   612 YVLATPASTQAALKEVLADAEKKEEEAKKAKEKEKEKEEA--------------GGKPDKVKVAK 662
                   ..:|.::|..:.||..|:..|:.|.|.|:.:.|              .|.|...:..:
  Rat   685 -------RHKADMEEKSSKAESGEKSKKRKKRKRKKNKSAPADSERGPKPEPPGSGSPAPPRRRR 742

  Fly   663 KIVKDMEKW---AKQLNQ-KKDYTAVAT-----------PQPILSD----TEAATTSRASQGAYA 708
            :...|.::.   |::.|. |||.....:           .:|..|.    |.|..:||:|..:..
  Rat   743 RARDDSQRRSLPAEEGNSGKKDDGGAGSGSQDHSGRKHKGEPPASSCQRRTSAKHSSRSSHRSQP 807

  Fly   709 DVG--------------------FSILEKKELGKLNDYVPEAGPPAISKLVGAYGGPSDSEDDNS 753
            ..|                    :|..|::|..:..:...|                .:.||::|
  Rat   808 SSGDEDSDNASSSHRPHQKSPSQYSEEEEEEEEEEEEEEEE----------------EEEEDEDS 856

  Fly   754 ANQKALEAS---------VGTKRAISDESDYVDFQKLTCLLCMRAFQS------LDILQKHLKMS 803
            .::.:...|         ..::|:.|..||....|  :|.....::..      .|..::|.|.|
  Rat   857 GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQ--SCYSRQHSYSDDSYSDYSDRSRRHSKRS 919

  Fly   804 NLHKENLD------KLKRNPAVEAGTDEGLS-------YRDRAKERRLKYGESDPPPPNRSRERF 855
            : ..::.|      :.||:....:..|..||       .|...:||....|.|.....:|||.:.
  Rat   920 H-DSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKR 983

  Fly   856 EQEIKTLQSRQKD---SFGATAAMPISSTNVGSRLMQKMGW------------------------ 893
            .....|..|.|:.   |...:.:....|...|||   |..|
  Rat   984 RSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSR---KGSWGHESPEERRSGRRDFIRSKIYRSQ 1045

  Fly   894 -------SEGQGLGKKNQGRTEIIEADG----RSNNVGLGNNTGHMAPGNDYKSYIKKMMKQRYE 947
                   ..|:|.|||..||.|..:..|    .||..|.|..:.......|..|...:::.::.:
  Rat  1046 SPHYFRSGRGEGHGKKEDGRGEDSKGAGLPSQNSNAGGTGRGSESDCSPEDKNSVTARLLLEKIQ 1110

  Fly   948 N 948
            :
  Rat  1111 S 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4896	NP_608583.5	U2AF_lg	74..>158	CDD:273727	19/97 (20%)
		RRM1_RBM5_like	211..291	CDD:409977	29/181 (16%)
		ZnF_RBZ	296..320	CDD:197784	4/33 (12%)
		RanBP2-type Zn finger	298..317	CDD:275376	4/28 (14%)
		RRM1_RRM2_RBM5_like	343..429	CDD:409752	14/85 (16%)
		OCRE_RBM5_like	562..617	CDD:293881	8/54 (15%)
		OCRE repeat 1	567..574	CDD:293881	1/6 (17%)
		OCRE repeat 2	575..582	CDD:293881	2/6 (33%)
		OCRE repeat 3	583..590	CDD:293881	0/6 (0%)
		OCRE repeat 4	591..598	CDD:293881	1/6 (17%)
		OCRE repeat 5	600..607	CDD:293881	0/6 (0%)
		G-patch	882..924	CDD:396249	18/76 (24%)
Gpatch8	NP_001385812.1	G-patch	40..82	CDD:396249	2/5 (40%)
		PRK03918	<82..>207	CDD:235175	26/126 (21%)
		zf-C2H2_jaz	136..163	CDD:432381	5/26 (19%)
		PTZ00449	<1054..1327	CDD:185628	15/58 (26%)