Protein Alignment CG4896 and Rbm10

DIOPT Version :10

• Sequence 1: NP_608583.5
• Gene: CG4896 / 33305
• FlyBaseID: FBgn0031319
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_063136351.1
• Gene: Rbm10 / 64510
• RGDID: 631366
• Length: 930
• Species: Rattus norvegicus
• Alignment Length: 1052
• Identity: 326/1052 - (30%)
• Similarity: 463/1052 - (44%)
• Gaps: 266/1052 - (25%)

  Fly    40 EYRRRNSRSRSRERSSHY-RNDRSPDRDLYRDLINEDYEDQGNYNSR----QNLDQRHGEDKYDR 99
            ||.||..|.   :|:..| ..|||.|             |.|...||    :::|.|    .|.|
  Rat     2 EYERRGGRG---DRTGRYGATDRSQD-------------DGGENRSRDHDYRDMDYR----SYPR 46

  Fly   100 RHADSQGRRDH-DSNYDKSGQDMDKDRDHRWKNYD-------RVSRERNHDDFDRGSERSSRSND 156
            .:...:|:.:: ||:.::|.:|          :|:       :..|.|.|.....|.....|..|
  Rat    47 EYGSQEGKHEYDDSSEEQSAED----------SYEASPGSETQRRRRRRHRHSPTGPPGFPRDGD 101

  Fly   157 QRQFNNNGNSNSSSSYR----DREKERDRDRRCSSDEDSDMASEFRQRGAYNSGSSVEPLNNIIL 217
            .|          ...||    :.|:|.|.:     :|:.:.||                 |.::|
  Rat   102 YR----------DQDYRTEQGEEEEEEDEE-----EEEEEKAS-----------------NIVML 134

  Fly   218 FGLKKHVTEADIMGELIKVDLEPTSIRVMRKQQTGASRCFAFVEFKTVEEATRWMELTQGVLQLG 282
            ..|.:..||.||.|:|....::...:|:||.:.:|.||.||||||..:::||||||..|..|.:.
  Rat   135 RMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNIL 199

  Fly   283 DHRVTMQYSHTR---ISDWTCIKCGASNFKRRFQCYMCNASRAESENALYGAGEGVD-------- 336
            ..:|:|.||..:   ..||.|.|||..|||||.:|:.|...::|:|..| ..|..:|
  Rat   200 GQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKL-PLGTRLDQQALPLGG 263

  Fly   337 -EISQ-------------ILTKK----------------IMLRGLDALTNEEGVLTALQQRLPEL 371
             |:||             :||.:                |:||.|:..:..:.:|.||   .|..
  Rat   264 RELSQGLLPLPQPYQAQGVLTSQALSQGSEPSSENANDTIILRNLNPHSTMDSILGAL---APYA 325

  Fly   372 AKTVSKVLVSRDALTNASRGICYLNFDTLIDSMNVFNGLTALDPPLTLDDKTVIVTYCIDSENRQ 436
            ..:.|.|.|.:|..|..:||..::...|::::..:...|.||.||||:|.||:.|.:...|: |.
  Rat   326 VLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSK-RD 389

  Fly   437 MMPAEGNFFRAGETAMSPSAITAA-YTLADVPRLAEYSASVYASNPLEHANYVQ-------YYTD 493
            |...||:  |....:::.:||.|| :.::...:..|.:.:.....|::::.|.|       ..||
  Rat   390 MASNEGS--RINAASVASTAIAAAQWAISQASQGGESTWAAPEEPPVDYSYYQQDEGYGSSQGTD 452

  Fly   494 -YYTTEISKNCRDRQVTEA---NSGA-----------AVALSAIQRKQRKV-------------- 529
             .|.....||.:...:|..   .|||           :|:|.|..|.|...
  Rat   453 SLYAHGYLKNTKGPGMTGTKGDTSGAGPETSLEGGTDSVSLQAFSRAQPGAAPGLYQQSAEGSSG 517

  Fly   530 ------SQMETTVSVTEAKVAFL-----------ARGESAPKGNDGKKYDTPDVSKYQYDETSGY 577
                  ||..|.:|....|....           |...:||:..  .:|..||||.|||||||||
  Rat   518 QGTATNSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAPESY--SQYPVPDVSTYQYDETSGY 580

  Fly   578 YYDHVTGLYYDAHSQYYYNNETGAYLYWDQKRSTYVLATPASTQAALKEVLADAEKKEEEAKKAK 642
            |||..||||||.:||||||.::..|||||.:|.||:   ||..|:      ||..|....:.|..
  Rat   581 YYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYI---PALEQS------ADGHKDTGASSKEG 636

  Fly   643 EKEKEKEEAGGKPDKVKVAKKIVKDMEKWAKQLN-QKKDYTAVATPQPILSDTEAATTSRASQGA 706
            :::|||.       |.|.|::|.||||:||:.|| ||:::.....|...|.|.|      ..:.|
  Rat   637 KEKKEKH-------KTKTAQQIAKDMERWARSLNKQKENFKNSFQPISALRDDE------RRESA 688

  Fly   707 YADVGFSILEKK-----------ELGKL-NDYVPEAGPPAISKLVGAYGGPSDSEDDNSANQKAL 759
            .||.|::|||||           :|.|| :|..|  .||  ..||.||.|.||||::....
  Rat   689 TADAGYAILEKKGALAERQHTSMDLPKLASDDRP--SPP--RGLVAAYSGESDSEEEQERG---- 745

  Fly   760 EASVGTKRAISDESDYVDFQKLTCLLCMRAFQSLDILQKHLKMSNLHKENLD-----KLKRN--P 817
                |.:|    |....|:|||.||||.|.|.|.:.|.:|.::|.|||:||:     .|..|  .
  Rat   746 ----GPER----EEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELE 802

  Fly   818 AVEAGTDEGLSYRDRAKERRLKYGESDPPPPNRSR--------ERFEQEIKTLQSRQKDSFGATA 874
            |:|....|.:.|||||.|||.|||..:||.|.|.:        ..|||.       .:|..|
  Rat   803 ALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQP-------TRDGLG--- 857

  Fly   875 AMPISSTNVGSRLMQKMGWSEGQGLGKKNQGRTEIIEADGRSNNVGLG--NNTGHMAPGNDYKSY 937
                 |.|:|||::|.|||.||.|||:|.||....|||..|....|||  .::..:.....||..
  Rat   858 -----SDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKET 917

  Fly   938 IKKMMKQRYENA 949
            :.|.|..|:..|
  Rat   918 LHKTMVTRFNEA 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4896	NP_608583.5	U2AF_lg	74..>158	CDD:273727	20/95 (21%)
		RRM1_RBM5_like	211..291	CDD:409977	31/79 (39%)
		ZnF_RBZ	296..320	CDD:197784	13/23 (57%)
		RanBP2-type Zn finger	298..317	CDD:275376	11/18 (61%)
		RRM1_RRM2_RBM5_like	343..429	CDD:409752	28/101 (28%)
		OCRE_RBM5_like	562..617	CDD:293881	36/54 (67%)
		OCRE repeat 1	567..574	CDD:293881	5/6 (83%)
		OCRE repeat 2	575..582	CDD:293881	6/6 (100%)
		OCRE repeat 3	583..590	CDD:293881	6/6 (100%)
		OCRE repeat 4	591..598	CDD:293881	6/6 (100%)
		OCRE repeat 5	600..607	CDD:293881	4/6 (67%)
		G-patch	882..924	CDD:396249	23/43 (53%)
Rbm10	XP_063136351.1	None