Protein Alignment CG4896 and rbm6

DIOPT Version :10

• Sequence 1: NP_608583.5
• Gene: CG4896 / 33305
• FlyBaseID: FBgn0031319
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_005166176.2
• Gene: rbm6 / 567058
• ZFINID: ZDB-GENE-050309-79
• Length: 1448
• Species: Danio rerio
• Alignment Length: 1103
• Identity: 258/1103 - (23%)
• Similarity: 407/1103 - (36%)
• Gaps: 327/1103 - (29%)

  Fly    33 ERSRDRNEYRRRNSRSRSRERSSHYRNDRSPDRDLYRDLINEDYEDQGNYNSRQ----------- 86
            |||:.:...|.|.|....:|.:...|::|.|....:......|:.      ||:
Zfish   480 ERSQFKERDRERPSAYLGKESTGFNRSEREPKHQHWEKNTPSDFP------SRELGTQKPPPIQM 538

  Fly    87 ----NLDQRHGEDKY--DR-----RHADSQGRRDH--DSNYDKSGQDMDKDRDHRWKNYDRVSRE 138
                |:..|.||..:  ||     |.|.:.||..:  |.|        ..:::|.:|:
Zfish   539 DPTLNVQGREGEKSWPVDREEKPERTAPAGGRPPYFQDKN--------SPNQEHHFKS------- 588

  Fly   139 RNHDDFDRGSERSSRSNDQRQFNNNGNSNSSSSYRDR--EKERDRDRRCSS-------------- 187
             |...|....:|:|....||:...:|.....|:..::  :..||.|.|..|
Zfish   589 -NRVPFKGSGDRASDQEPQRESLMSGPKEMQSNRGEQLDQDYRDIDYRTGSGRKYDYSLGDLHGL 652

  Fly   188 ---------------DEDSDMASEFRQRGAYNSGSSVEPLNNIILFGLKKHVTEADIMGELIKVD 237
                           |:......::|..|..:     :..|.|.:.|:.|:.|...|:|.....|
Zfish   653 EKDVKESKLVPVERVDDSGSQDQDYRSAGVQD-----KITNTIAISGIPKNATMQQILGAFAVRD 712

  Fly   238 LEPTSIRVMRKQQTGASRCFAFVEFKTVEEATRWMELTQGVLQLGDHRVTMQYSHTRISDWTCIK 302
            ..|.....::....|.|...|:|||..:|:|..:||..||.:::||....::|..   ||
Zfish   713 GVPMQGMKIKDVVPGYSFDTAYVEFLNLEDAVHFMESNQGSVKVGDKTALLKYVQ---SD----- 769

  Fly   303 CGASNFKRRFQCYMCNASRA---------------ESENA----LYGAGEGVDEISQILTKKIML 348
               .|.|.:.......|:.|               :.|.|    |..|.:||.:.|..||.:...
Zfish   770 ---KNGKEQLHEPPTKATPASDDGLLPNPVPPPNKQEETAVKPLLDAASQGVWQRSSNLTPEAWQ 831

  Fly   349 RGLD--------------ALTNEEGVLTALQQRLPELAKTVSKVLVSRDALTNASRGICYLNFDT 399
            :.:|              ..||:......||...|...:  ||.::.::.|..           |
Zfish   832 QQVDQQQQQQELEQQPTEEWTNQRASRQNLQYSDPVFKE--SKTMIIKNILPT-----------T 883

  Fly   400 LIDSMNVFNGLTALDPPLTLDDKTVIVT---------YC-IDSENRQMMPAEGNFFRAGETAMSP 454
            .::::     |.||||...||::.|.:.         :| :|.::.:      :..|..|....|
Zfish   884 TVETI-----LKALDPFAYLDERNVRLVKGKSPGSKCFCFVDMDSHE------HVTRLVELLTKP 937

  Fly   455 SAITAAYTLADVPRLAEYSASVYA--SNPLEHANY---------------------------VQY 490
            ..|     :.|..|       |||  :.||::.||                           .|:
Zfish   938 RPI-----MIDGVR-------VYAEVAKPLKNQNYRRDNEKANTSLLGLPPDVIKQQPYQQPQQF 990

  Fly   491 YTDYYTTEISKNCRDRQVTEAN---SGAAVALSAIQR--KQRKVSQMETTVSVTEAKVAFL--AR 548
            |.....|.:........:..|:   |..||..|::.:  .....|.:..||...|.:...|  |.
Zfish   991 YPQPVLTAVGAASIQGDLIGADATLSSVAVPSSSLTQGVMYSNKSAIAQTVQTAEQQAPALSDAA 1055

  Fly   549 GESAPKGNDGKKY--DTPDVSKYQYDETSGYYYDHVTGLYYDAHSQYYYNNETGAYLYWDQKRST 611
            ...|....||..|  :.||:|.:.||.|||:|||..|.||||.:|:|:|:.:...|||||....|
Zfish  1056 VSGAADSIDGYNYGSEAPDLSAFLYDATSGFYYDPQTTLYYDPNSRYFYDAQNQQYLYWDSSLKT 1120

  Fly   612 YVLATPASTQA--------------------------------ALKEVLADAEKKEEEAKKAKEK 644
            |:....:||..                                |:.|.|.:...:||..::.:::
Zfish  1121 YIPVQSSSTDGQNVPEVPAPEVPAPVTPVAEVIAVPIKEEEAKAVSEALPEVRVEEEPGQRGEKR 1185

  Fly   645 EKEKEEAGGKPDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILSDTEAATTSRASQGAYAD 709
            ||||||   ||..: .|.||:||||:|||..|.||:  :|..|.|:|...:....|:|     ||
Zfish  1186 EKEKEE---KPRSL-AAFKIMKDMERWAKIQNSKKE--SVRAPSPVLKSGDDHRPSKA-----AD 1239

  Fly   710 VGFSILEKK----ELGKLNDYVPEAGPP------------AISKLVGAYGGPSDSEDDNSAN-QK 757
            ..|:|.|:|    ||.|    .|.|.|.            ::..|...||..||.|::...: |:
Zfish  1240 AAFAIFERKTGADELFK----KPLAPPKQKDEKSSKRPMGSLGMLAADYGAGSDEEEEEKHDKQE 1300

  Fly   758 ALEASVGTKRAISDESDYVDFQKLTCLLCMRAFQSLDILQKHLKMSNLHKENLD---KLKRNP-A 818
            |...:....:|...|....|::|:.||||.|.|.:.|.|.:|.::|:|||:|::   |:||:. .
Zfish  1301 ASRPAKSQPQADEKEDRLTDWKKMACLLCRRQFPNKDALIRHQQLSDLHKQNMEIHLKIKRSKRE 1365

  Fly   819 VEAGTDEGLSYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKDSFGATAAMPISSTNV 883
            :||       ..::.||.:.|...|.|....|..:      .|.....:|||..
Zfish  1366 LEA-------LENQEKEMKTKAPGSSPEAKRRKPQ------NTWAGSSRDSFKG----------- 1406

  Fly   884 GSRLMQKMGWSEGQGLGKKNQGRTEIIEADGRSNNVGLGNNTGHMAPGNDYKSYIKKMMKQRY 946
                      ||..|||.:...|        :.....:.|:.       .||..::|.|..|:
Zfish  1407 ----------SERPGLGLETTER--------KKKEPVVWNHA-------TYKQAVRKAMFARF 1444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4896	NP_608583.5	U2AF_lg	74..>158	CDD:273727	21/107 (20%)
		RRM1_RBM5_like	211..291	CDD:409977	23/79 (29%)
		ZnF_RBZ	296..320	CDD:197784	4/23 (17%)
		RanBP2-type Zn finger	298..317	CDD:275376	2/18 (11%)
		RRM1_RRM2_RBM5_like	343..429	CDD:409752	19/108 (18%)
		OCRE_RBM5_like	562..617	CDD:293881	26/54 (48%)
		OCRE repeat 1	567..574	CDD:293881	3/6 (50%)
		OCRE repeat 2	575..582	CDD:293881	5/6 (83%)
		OCRE repeat 3	583..590	CDD:293881	5/6 (83%)
		OCRE repeat 4	591..598	CDD:293881	3/6 (50%)
		OCRE repeat 5	600..607	CDD:293881	4/6 (67%)
		G-patch	882..924	CDD:396249	6/41 (15%)
rbm6	XP_005166176.2	RRM_SF	688..765	CDD:473069	23/76 (30%)
		RRM_SF	870..954	CDD:473069	23/119 (19%)
		OCRE_RBM5_like	1072..1125	CDD:293881	26/52 (50%)
		OCRE repeat 1	1076..1083	CDD:293881	3/6 (50%)
		OCRE repeat 2	1084..1091	CDD:293881	5/6 (83%)
		OCRE repeat 3	1092..1099	CDD:293881	5/6 (83%)
		OCRE repeat 4	1100..1107	CDD:293881	3/6 (50%)
		OCRE repeat 5	1109..1116	CDD:293881	4/6 (67%)