DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4896 and CG31550

DIOPT Version :9

Sequence 1:	NP_608583.5	Gene:	CG4896 / 33305	FlyBaseID:	FBgn0031319	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	NP_001262285.1	Gene:	CG31550 / 40661	FlyBaseID:	FBgn0051550	Length:	835	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	75/379 - (19%)
Similarity:	136/379 - (35%)	Gaps:	83/379 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   625 KEVLADAEKKEEEAKKAK------------EKEKEKEEAGGKPDKVKVAKKIVKDMEKWAKQLNQ 677
            |:..|:.:::.|..|.::            ::.:|::.:....||......|..|.:...:.:..
  Fly   461 KQQRAERQREREHQKLSRDHQPQATEQTDAQQHREEQHSNSAADKYDPESAISADFDSDDEYMRG 525

  Fly   678 KKDYTAVATPQPI-----LSDTEAATTSRASQGAYADVGFSILE--------------KKELGKL 723
            ..|.......:.|     |||.|......|:.|...|......:              |...|:.
  Fly   526 MMDRNRDNIKRRIECRNELSDEERREREEAASGEPPDGDDQDDQDDKESQRQRRKRERKSRWGEK 590

  Fly   724 NDYVPEAGPPAISKLVGAYGGPSDSEDDNSANQKALEASVGTKRAISDESDYVDFQKLTCLLCMR 788
            ...:|.      |...|.:|         :.|:..|.....|..|:      :.:.:|.......
  Fly   591 EQQLPS------SSTSGNFG---------NQNKPILSGITRTDPAL------LQYARLNYGSTQL 634

  Fly   789 AFQSLDILQKHLKMSNLH------KENLDKLKR----------NPAVEAGTDE-----------G 826
            :.:.....::|.|::.|:      ::.:|:|.|          :..:|.||.|           .
  Fly   635 SEEQWKQCEEHYKVNLLYQDMMRKRQEIDRLARGGKFKYEYDSDEDIEGGTWEHKLRTAEMEATS 699

  Fly   827 LSYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKDSFGATAAMPISSTNVGSRLMQKM 891
            |......|:...|:...|..||...::..||......:||.| ........:...|:|.:::||:
  Fly   700 LWANALTKQSEGKHHIGDFLPPEELKKFMEQYEAKKNNRQPD-LSDYKEYKLKEDNIGFQMLQKL 763

  Fly   892 GWSEGQGLGKKNQGRTE-IIEADGRSNNVGLGNNTGHMAP--GNDYKSYIKKMM 942
            ||.||||||:...|..: :.:|..|..|.|||.::.....  .|:|.:|.|:||
  Fly   764 GWKEGQGLGQDGAGIVDPVNKAPQRDGNQGLGVSSAAQPEDCDNEYDAYRKRMM 817

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4896	NP_608583.5	DUF1777	91..>158	CDD:285811
		RRM1_RBM5_like	211..291	CDD:241005
		ZnF_RBZ	296..320	CDD:197784
		RanBP2-type Zn finger	298..317	CDD:275376
		RRM1_RRM2_RBM5_like	343..429	CDD:240759
		OCRE_RBM5_like	562..617	CDD:293881
		OCRE repeat 1	567..574	CDD:293881
		OCRE repeat 2	575..582	CDD:293881
		OCRE repeat 3	583..590	CDD:293881
		OCRE repeat 4	591..598	CDD:293881
		OCRE repeat 5	600..607	CDD:293881
		G-patch	882..922	CDD:279867	17/40 (43%)
CG31550	NP_001262285.1	G-patch	753..797	CDD:279867	19/43 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786674at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920