DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4896 and gpatch2

DIOPT Version :9

Sequence 1:	NP_608583.5	Gene:	CG4896 / 33305	FlyBaseID:	FBgn0031319	Length:	949	Species:	Drosophila melanogaster
Sequence 2:	XP_002936068.3	Gene:	gpatch2 / 100379758	XenbaseID:	XB-GENE-987864	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	379	Identity:	82/379 - (21%)
Similarity:	140/379 - (36%)	Gaps:	118/379 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   617 PASTQAAL-----KEVLADAEKKE-EEAKKAKEKEKEKEEAGGK-----PDKVKVAKKIVKDMEK 670
            ||...:.|     ::...|.|.|. :..:.||.|.|:::.:..:     ||     :.:|.:.|:
Frog   168 PAEVTSTLTLYQSRDQSMDNESKHYQHMELAKSKNKKRKISAPRRGPEIPD-----EGVVVEGEE 227

  Fly   671 WAKQLNQKKDYTAVATPQPILSDTEAATTSRASQGAYADVGFSILEKKELGKLND-------YVP 728
            .:.....|.:|.........:||:|:::.|.:..|.:.:         :.|:..|       |..
Frog   228 ISHGNKDKMEYEEQKVSDENMSDSESSSISSSDAGLFTN---------DEGRQGDDEQSDWFYES 283

  Fly   729 EAGPPAISKLVGAYGG----PSDSEDDNSANQKALEASVGTKRAISDESDYVDFQKLTCLLCMRA 789
            |:|        ||.|.    |...::|::..||.:...|       .||.......|......|.
Frog   284 ESG--------GACGMTGVIPWWEQEDSAELQKQMPDPV-------FESILTGSFPLMSQSAQRG 333

  Fly   790 FQSLDILQKHLKMSNLHKENLDKLKR-----NPAVEAGTDEGLSYRDRAKERRLKYGESDP---- 845
            ||:        ::|:||......:::     ||.:   ...|.|     ...||.:...||
Frog   334 FQA--------RLSHLHAMQARSIRKSAVNPNPLI---ASPGAS-----NTERLVHFSPDPHHHD 382

  Fly   846 ---PP-----------PNRSRERFEQ--EIKT----------------LQSRQKDS--------- 869
               .|           .|||....::  .:||                ::.|:|::
Frog   383 HWFSPGARKDHSQLLRDNRSDRGHKKNCSVKTASRQTSVHLGSLFIGDIKRRRKNANPLPGPTVS 447

  Fly   870 -FGATAAMPISSTNVGSRLMQKMGWSEGQGLGKKNQGRTEIIEADGRSNNVGLG 922
             |...:|.||...|:|:|::|.|||:.|.|||...:|.:|.|.|..|...:|||
Frog   448 GFIGESAQPIPDNNIGNRMLQNMGWTPGTGLGPDGKGISEPIRALQRPKGLGLG 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4896	NP_608583.5	DUF1777	91..>158	CDD:285811
		RRM1_RBM5_like	211..291	CDD:241005
		ZnF_RBZ	296..320	CDD:197784
		RanBP2-type Zn finger	298..317	CDD:275376
		RRM1_RRM2_RBM5_like	343..429	CDD:240759
		OCRE_RBM5_like	562..617	CDD:293881	82/379 (22%)
		OCRE repeat 1	567..574	CDD:293881
		OCRE repeat 2	575..582	CDD:293881
		OCRE repeat 3	583..590	CDD:293881
		OCRE repeat 4	591..598	CDD:293881
		OCRE repeat 5	600..607	CDD:293881
		G-patch	882..922	CDD:279867	17/39 (44%)
gpatch2	XP_002936068.3	G-patch	460..501	CDD:396249	17/40 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910