DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4887 and gpatch2

DIOPT Version :9

Sequence 1:NP_001259859.1 Gene:CG4887 / 33304 FlyBaseID:FBgn0031318 Length:1004 Species:Drosophila melanogaster
Sequence 2:XP_002936068.3 Gene:gpatch2 / 100379758 XenbaseID:XB-GENE-987864 Length:503 Species:Xenopus tropicalis


Alignment Length:635 Identity:125/635 - (19%)
Similarity:198/635 - (31%) Gaps:229/635 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   430 TQASRGICYLHFDTLVDSMNVHNALTALDPP--------LTLDDRVVAIT--------------- 471
            |:|::|..: ||...::.: ||:.::||:..        ....|...:|:               
 Frog     9 TRANKGTSW-HFSKTMEEL-VHDLVSALEESSEQARGCFADTGDHSRSISCLLKRQARKRRGRKR 71

  Fly   472 ------------YCI------DLEEQ----QALPKNPKE---------LAVKDSTVNSGNISAVS 505
                        :|:      .||||    :....|.|:         ||.:..:.|..||....
 Frog    72 RSDNTHHPWETGHCLSDGSDSSLEEQNKDYRECTSNQKKDSDSDDQLLLAKRRPSSNITNIRGKR 136

  Fly   506 P----SGLG----GNYTL---ADVPRLAEYSASLYASNPAEHAYYVQYYTEYYTADINKNNRDSH 559
            |    |.|.    |:.||   ..|.|:|       ...|||   .....|.|.:.|.:.:|...|
 Frog   137 PLWHESDLVVDTLGSRTLRRRRKVKRMA-------IDPPAE---VTSTLTLYQSRDQSMDNESKH 191

  Fly   560 LTEANSGAAVALSAIQRKQKKMSSIETTITAAATAAAQAAAQV-KATLAAQVASAPKGNDGKI-Y 622
            ...      :.|:..:.|::|:|            |.:...:: ...:..:......||..|: |
 Frog   192 YQH------MELAKSKNKKRKIS------------APRRGPEIPDEGVVVEGEEISHGNKDKMEY 238

  Fly   623 PTPDVT-QYQYDETSGYYYDSTTGLYYN--------AHSQYYYNNE-------TGAYLYWDQRRS 671
            ....|: :...|..|.....|..||:.|        ..|.::|.:|       ||...:|:|..|
 Frog   239 EEQKVSDENMSDSESSSISSSDAGLFTNDEGRQGDDEQSDWFYESESGGACGMTGVIPWWEQEDS 303

  Fly   672 TYVLATPASTQAALQEVLADAEQKGEEESKKAKEKEGGNKHDKVKVAKKIVKDMEKWAKQLNQKK 736
                       |.||                                           ||:    
 Frog   304 -----------AELQ-------------------------------------------KQM---- 310

  Fly   737 DYTAVATPQP----ILANEVATTSRGNQGGYADVGFSILEKKERGKLNDYAPNPTVGPMNKLVNA 797
                   |.|    ||.......|:..|.|: ....|.|...:...:...|.||     |.|: |
 Frog   311 -------PDPVFESILTGSFPLMSQSAQRGF-QARLSHLHAMQARSIRKSAVNP-----NPLI-A 361

  Fly   798 YGGTSDSEEDNAASSQNTQSSAVVSGGGGAEESDYVDFHKLTCLLCKRAFQSLEILQKHLKMSTL 862
            ..|.|::|.....|..........|.|...:.|.                     |.:..:....
 Frog   362 SPGASNTERLVHFSPDPHHHDHWFSPGARKDHSQ---------------------LLRDNRSDRG 405

  Fly   863 HKENLAKLNQNTSSSIEEALAYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKQSTSA 927
            ||:|.:....:..:|:.....:....|.||    ::..|.|..:...|..|              
 Frog   406 HKKNCSVKTASRQTSVHLGSLFIGDIKRRR----KNANPLPGPTVSGFIGE-------------- 452

  Fly   928 TPAMPISSSNVGSRLLQKMGWSEGQGLGRKNQGRTQIIEADGRSNYVGLG 977
             .|.||..:|:|:|:||.|||:.|.|||...:|.::.|.|..|...:|||
 Frog   453 -SAQPIPDNNIGNRMLQNMGWTPGTGLGPDGKGISEPIRALQRPKGLGLG 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4887NP_001259859.1 DUF1777 115..>196 CDD:285811
RRM_SF 255..335 CDD:302621
ZnF_RBZ 341..364 CDD:197784
RanBP2-type Zn finger 342..361 CDD:275375
RRM1_RRM2_RBM5_like 387..473 CDD:240759 11/77 (14%)
OCRE_RBM5_like 623..678 CDD:293881 15/70 (21%)
OCRE repeat 1 628..635 CDD:293881 1/7 (14%)
OCRE repeat 2 636..643 CDD:293881 1/6 (17%)
OCRE repeat 3 644..651 CDD:293881 3/14 (21%)
OCRE repeat 4 652..659 CDD:293881 2/6 (33%)
OCRE repeat 5 661..668 CDD:293881 2/6 (33%)
G-patch 935..979 CDD:279867 19/43 (44%)
gpatch2XP_002936068.3 G-patch 460..501 CDD:396249 17/40 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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