Protein Alignment Charon and BCL3

DIOPT Version :10

• Sequence 1: NP_608581.2
• Gene: Charon / 33303
• FlyBaseID: FBgn0031317
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_054177662.1
• Gene: BCL3 / 602
• HGNCID: 998
• Length: 696
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 59/243 - (24%)
• Similarity: 90/243 - (37%)
• Gaps: 75/243 - (30%)

  Fly   262 EEGLLPIHEEILHGDVYGVKRQIFVCCHAKMDINELLTRDGEDCLELALTNDTDTEIVSLILDAR 326
            |:|..|:|..::.|::..|.|.:           .|..:.|.:                  ||
Human   355 EDGDTPLHIAVVQGNLPAVHRLV-----------NLFQQGGRE------------------LD-- 388

  Fly   327 MMTDHLYEN-SNTALHLAVINHINIESIRLLLRRIDLNSLLLTNDDGYTVLHLAVRNNQFLVVEA 390
                 :|.| ..|.||||||.  .:.|:..||.....:.:.| :..|.|..|||..:.....:.|
Human   389 -----IYNNLRQTPLHLAVIT--TLPSVVRLLVTAGASPMAL-DRHGQTAAHLACEHRSPTCLRA 445

  Fly   391 ILDSIDERELGETVYRRTLEAANPNEWDEKGFAKYYD----------RACERLELNKTLLKNRAH 445
            :|||                 |.|...|.:  |:.||          ..|:  |..:.||:..|.
Human   446 LLDS-----------------AAPGTLDLE--ARNYDGLTALHVAVNTECQ--ETVQLLLERGAD 489

  Fly   446 KRDVINASEARGGNPPLFYAVEGEQEHLCYFLLAHLADPDEENLSGHS 493
                |:|.:.:.|..||.:|||.....:...||.|.|:.:.:..||.|
Human   490 ----IDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSS 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Charon	NP_608581.2	ANKYR	290..513	CDD:440430	52/215 (24%)
		ANK repeat	301..333	CDD:293786	3/31 (10%)
		ANK repeat	335..369	CDD:293786	12/34 (35%)
		ANK repeat	371..455	CDD:293786	22/93 (24%)
		ANK repeat	457..488	CDD:293786	10/30 (33%)
BCL3	XP_054177662.1	PHA03247	<97..344	CDD:223021
		ANKYR	343..571	CDD:440430	59/243 (24%)
		ANK repeat	356..391	CDD:293786	10/70 (14%)
		ANK repeat	393..424	CDD:293786	11/33 (33%)
		ANK repeat	426..461	CDD:293786	13/53 (25%)
		ANK repeat	463..494	CDD:293786	8/36 (22%)
		ANK repeat	497..528	CDD:293786	10/30 (33%)
		ANK repeat	530..561	CDD:293786	3/4 (75%)