Protein Alignment Tango14 and Nus1

DIOPT Version :10

• Sequence 1: NP_608577.2
• Gene: Tango14 / 33298
• FlyBaseID: FBgn0031312
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_084526.1
• Gene: Nus1 / 52014
• MGIID: 1196365
• Length: 297
• Species: Mus musculus
• Alignment Length: 328
• Identity: 84/328 - (25%)
• Similarity: 133/328 - (40%)
• Gaps: 98/328 - (29%)

  Fly    16 LVGGYELMWRLRERL--------NALAVR--SYD-LWR--SKAAREA------------------ 49
            :.|.|||:||:...|        :.|.||  ::: :||  .:||..|
Mouse     1 MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRN 65

  Fly    50 --HER-------------------RVLADCRSQLTKTPQHLVLVIS-----PVDAGVDAVLLSRI 88
              |.|                   |..||.|| |.|.|.|:.|:::     |..:.:.::::
Mouse    66 RRHHRHPHGGPGPGPGPAATHPRLRWRADVRS-LQKLPVHMGLLVTEEVQEPSFSDIASLVV--- 126

  Fly    89 FDFALDVGIKHVSLYD-----RRTKGRGYVDMADLCRSTNADTG-SCLKWPPVASPSKLENQPKN 147
              :.:.|||.::|:||     :|...|   .|.::.:......| .|.|:    |.....:..|:
Mouse   127 --WCMAVGISYISVYDHQGIFKRNNSR---LMDEILKQQQELLGQDCSKY----SAEFANSNDKD 182

  Fly   148 GQKTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDML 212
            .|..|       .|. .:..:|..||.   ||:.|     :..:..|.:.:|:|:. |:...|:|
Mouse   183 DQDLN-------CPS-AVKVLSPEDGK---ADIVR-----AAQDFCQLVAQQQRKP-TDLDVDLL 230

  Fly   213 SKRL---GFEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQ 274
            ...|   ||  |:|:|.:.|.....|.|.|||..|.||..:.||..:...|.|.|.|.:|:.|||
Mouse   231 GSLLSSHGF--PDPDLVLKFGPVDSTLGFLPWQIRLTEIVSLPSHLNISYEDFFSALRQYAACEQ 293

  Fly   275 RWG 277
            |.|
Mouse   294 RLG 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango14	NP_608577.2	None
Nus1	NP_084526.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..86		2/22 (9%)
		UppS	<200..297	CDD:439791	37/108 (34%)
		RXG motif, crucial for prenyltransferase activity. /evidence=ECO:0000250|UniProtKB:Q96E22	294..296		1/1 (100%)