Protein Alignment Tfb4 and GTF2H3

DIOPT Version :9

• Sequence 1: NP_608574.2
• Gene: Tfb4 / 33294
• FlyBaseID: FBgn0031309
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_001507.2
• Gene: GTF2H3 / 2967
• HGNCID: 4657
• Length: 308
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 137/299 - (45%)
• Similarity: 182/299 - (60%)
• Gaps: 17/299 - (5%)

  Fly    12 ESCIDLLVIVLDTNP---SQHFVRQNPQNLTQILEAVIAFGNAHLMQKAQNKLAVVSCSHHATNF 73
            |..::|||||:|.||   .:..::::...|::.::||:..||:||.....|||||::.....:.|
Human     5 EDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRF 69

  Fly    74 LYP-----------LPRRQVELR---QVDGQYEAFNLVEKTVKQQLGSILMNAPRLSAPCESLLA 124
            |||           .|....|..   ..||:||......:.:.:::..::..:.......|:|||
Human    70 LYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTETLLA 134

  Fly   125 GSMSMALCYISRLQRNLAPGVKMHSRILVVTGSNECASQYMTFMNVFFTAQKLGITIDTCALDKT 189
            ||::.|||||.|:.:.:....:|.|||||:..:.:.|.|||.||||.|.|||..|.||.|.||..
Human   135 GSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSD 199

  Fly   190 LSLLQQGCDITSGQFLKVTQLDGLLQYLLWVFLPAPQIRHKLVLPPPPKVDYRASCFCHRELIDI 254
            ..||||.||||.|.:|||.|:..|||||||||||....|.:|:||||..|||||:|||||.||:|
Human   200 SGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEI 264

  Fly   255 GYVCSVCLSVFCKYSPICTTCHTIFKNPGPLPIKGKKKK 293
            |||||||||:||.:|||||||.|.||...|..:|.||||
Human   265 GYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKK 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tfb4	NP_608574.2	Tfb4	15..276	CDD:281798	126/277 (45%)
GTF2H3	NP_001507.2	tfb4	7..289	CDD:273181	128/281 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151815
Domainoid	1	1.000	248	1.000	Domainoid score	I2152
eggNOG	1	0.900	-	-		E1_COG5242
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1160
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3094
Isobase	1	0.950	-	0	Normalized mean entropy	S1938
OMA	1	1.010	-	-		QHG56022
OrthoDB	1	1.010	-	-		D1220881at2759
OrthoFinder	1	1.000	-	-		FOG0004351
OrthoInspector	1	1.000	-	-		oto89117
orthoMCL	1	0.900	-	-		OOG6_103072
Panther	1	1.100	-	-	LDO	PTHR12831
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3069
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720