DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and SEO1

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_009333.1	Gene:	SEO1 / 851230	SGDID:	S000000062	Length:	593	Species:	Saccharomyces cerevisiae

Alignment Length:	478	Identity:	95/478 - (19%)
Similarity:	175/478 - (36%)	Gaps:	112/478 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAINVVCTLLTPVF 155
            |:...||..|..::.:...::  |..|.::.|:|..          :.|..:.:|.|...|...:
Yeast   162 VSGMKEDLGFQGNDLVHTQVM--YTVGNIIFQLPFL----------IYLNKLPLNYVLPSLDLCW 214

  Fly   156 TELHYGG--------LILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVG-----TSA 207
            :.|..|.        |..:|...|.....|:.|...:..|:....|.:..|...|:|     .||
Yeast   215 SLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSA 279

  Fly   208 G---TALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNK--QRFISLEERQMITS 267
            |   :|:...|.||...: ||...|.:...:|.:..|:....:..:|..  ..|::.:|.::...
Yeast   280 GGIQSAVYSSLNGVNGLE-GWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARK 343

  Fly   268 SLGTEQ--KTEHHPAV----PWGKVFTSVPFWAILIAHTCSNFGW---------YMFLIEIPFYM 317
            .|...|  |::....|    .|..:|:.   |.|.|....:.|.|         |:      .::
Yeast   344 RLKENQTGKSDFETKVFDIKLWKTIFSD---WKIYILTLWNIFCWNDSNVSSGAYL------LWL 399

  Fly   318 KQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAK--GKITTTVARKTATSICT---LIPG 377
            |.:.::::.....||.:.....:::.:..|.:.|.|.::  ..|.|.|......||..   :..|
Yeast   400 KSLKRYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEG 464

  Fly   378 V---CLLVLCYIG--------------CR---HYEAVSVMSVGIVAMGSMFSGFLSNHI---DIA 419
            .   ..::.|: |              ||   ...|::::::.|:|..|  :.::|..:   :.|
Yeast   465 AKWFAFMLQCF-GWAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSS--TAWISVLVWKTEEA 526

  Fly   420 PNFAGTLVALTNTAATLPGIVVPLFV--GFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSG 482
            |.:   |...|.||.:...:.:..||  .|..:..:|.....     .|||:..:        .|
Yeast   527 PRY---LKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKKN-----GIVLYNSK--------HG 575

  Fly   483 SEQPWNKAGTPKDPE---AKDEK 502
            .|:|     |.||.|   ..|||
Yeast   576 VEKP-----TSKDVETLSVSDEK 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	88/460 (19%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	82/441 (19%)
SEO1	NP_009333.1	MFS_FEN2_like	134..548	CDD:340885	78/413 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000