DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS3 and slc17a5

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	486	Identity:	173/486 - (35%)
Similarity:	258/486 - (53%)	Gaps:	33/486 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PAKGSILGKLVP----ARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHG 66
            |||       ||    |||.|||:..:|..::|.|:||||||:|.|||.|
Frog    30 PAK-------VPVCCSARYNLALMALLGFFMLYALRVNLSVALVDMVNST--------------- 72

  Fly    67 SVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAEN 131
            |....|.:.....:..:.|....|.|.:    .:||....||.:|..:|:||:::|||..:||..
Frog    73 STPRENTTANICPDHTSAPAVLHNSTGQ----KYDWDANTQGWILGSFFYGYILTQIPGGYVAGK 133

  Fly   132 FSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMV 196
            ...|.::.|.:....|.|||||:..:...|.||.:|.|||:|.|.:|||||.|.|.||||.||..
Frog   134 IGGKQLLGFGILGTAVFTLLTPLAADFGAGCLIAVRALEGLGEGVTFPAMHAMWARWAPPLERSR 198

  Fly   197 MSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEE 261
            :.::.|.|...||.:|:.::|:......|..|||:.|.|..:|.::|..||.|.|...|.|:..|
Frog   199 LLSLSYAGAQLGTVVSLPVSGLICYYMDWIYVFYIFGTLGVLWFIMWCFLVSDTPQSHRSITDSE 263

  Fly   262 RQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVA 326
            ::.|..:|  :.:..:..:||...:..|:|.|||::||...|:.:|..|..:|.|||::|:||..
Frog   264 KEYILYTL--QNQLSYRKSVPCCAMMKSLPLWAIIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQ 326

  Fly   327 SNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHY 391
            .|..||||||....:|.|..|.:.|.|:.|..|:|.|.||...::..|.|.:.||...|.||.:.
Frog   327 ENGFLSALPYLGCWVFMIMAGVIADCLREKLNISTKVVRKIFNTLGMLGPAIFLLAAGYTGCNYS 391

  Fly   392 EAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIG 456
            .||..:::.....|...:|:..||:||||:|||.|:.:|||.||:||:|.|:....:|..| .:.
Frog   392 LAVVFLTLSTTLGGFSVAGYGINHLDIAPSFAGLLLGITNTFATIPGMVGPVIAKALTHDN-TVE 455

  Fly   457 AWRIIFGVTIVLFALEFLVFVFLGSGSEQPW 487
            .|:|:|.:...:.....:.|:...||:.|.|
Frog   456 QWQIVFYIAAAINFFGAIFFIIFASGNVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	167/469 (36%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	139/378 (37%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	160/444 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378598at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010