Protein Alignment MFS3 and Slc17a7

DIOPT Version :10

• Sequence 1: NP_608572.1
• Gene: MFS3 / 33292
• FlyBaseID: FBgn0031307
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_892038.2
• Gene: Slc17a7 / 72961
• MGIID: 1920211
• Length: 560
• Species: Mus musculus
• Alignment Length: 523
• Identity: 160/523 - (30%)
• Similarity: 266/523 - (50%)
• Gaps: 69/523 - (13%)

  Fly    16 VPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVE 80
            :|.||::|::..:|..|.:|::.||.||:|:|||::.  .|     .|||  |::..|.
Mouse    59 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNST--TH-----RGGH--VVVQKAQ------ 108

  Fly    81 ECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAIN 145
                               |:|.....|.:...:||||:|:|||...:.:.|:|..|..|::...
Mouse   109 -------------------FNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVAT 154

  Fly   146 VVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGTA 210
            ....:|.|....:|||.:|.:|:|:|:..|.::||.|.:.:.||||.||..::|..:.|:.||..
Mouse   155 STLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAV 219

  Fly   211 LSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSLGTEQK- 274
            :::.||||.....||.|||||.|:....|.|.|:::..::|.....||.|||:.|..::|...|
Mouse   220 VAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKL 284

  Fly   275 ----TEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVASNAALSALP 335
                |:.:  .||.:.|||:|.:||::|:.|.::.:|:.||..|.|.::|..|.::....:||||
Mouse   285 MNPVTKFN--TPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALP 347

  Fly   336 YFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVS----V 396
            :..|.|.....|::.|.|:::..::||..||...  |... |:...:|..:|..|.:.|:    |
Mouse   348 HLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMN--CGGF-GMEATLLLVVGYSHSKGVAISFLV 409

  Fly   397 MSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIGAWRII 461
            ::||.  .|...|||..||:||||.:|..|:.::|...||.|:|.|:.||.:|| ::....|:.:
Mouse   410 LAVGF--SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTK-HKTREEWQYV 471

  Fly   462 FGVTIVLFALEFLVFVFLGSGSEQPWNK-----------------AGTPKDPEAKDEKTPLKELP 509
            |.:..::.....:.:....||.:|||.:                 ||: .:.|.:||..|....|
Mouse   472 FLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGS-DESEMEDEAEPPGAPP 535

  Fly   510 TKP 512
            ..|
Mouse   536 APP 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	MFS_SLC17	23..480	CDD:340876	144/465 (31%)
Slc17a7	NP_892038.2	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	144/465 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		9/43 (21%)