DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	147/485 - (30%)
Similarity:	232/485 - (47%)	Gaps:	40/485 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVEECN 83
            |:.||.:..:....||..::|||:|:.||||.||..:|              :|||    :|  .
  Rat    36 RHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTAASSH--------------ANAS----IE--R 80

  Fly    84 PPGGAS---NVTAKVEDGP-FDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAI 144
            |...:.   |.|.:....| :||:..:||.|||...:|..::.||..:||..|.||:|:...:.:
  Rat    81 PTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYVVGLGLLV 145

  Fly   145 NVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGT 209
            :.|.||..|:..|.....||::||::|:.........:.|.|.||||.||..:.||...|:..||
  Rat   146 SSVLTLFIPLAAEAGVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIAASGSMLGT 210

  Fly   210 ALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSLGTEQK 274
            .|.::..|:.....||..:||:.|.:.|...|||..||.|:|....|||..|::.|..||..|..
  Rat   211 FLVLIAGGLLCQALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKRYIMCSLAQEDC 275

  Fly   275 TEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLI--EIPFYMKQVLKFNVASNAALSALPYF 337
            :... ::|...:..|:|.|||::::.|..  |.:|.|  ..|.|:..||:.|:..:..|||||:.
  Rat   276 SLGW-SLPIKAMVKSLPLWAIVVSYFCEY--WLLFTIMAYTPTYISSVLQANLRDSGILSALPFM 337

  Fly   338 PMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVSVMSVGIV 402
            ...:..|..|.|.|.|.::..:.....||..|::..|:....|:.|.::.    .::|. ::..:
  Rat   338 FGCVCIILGGLLADFLLSRNILRLVTIRKLFTALGVLVSSGILVPLPWVS----SSLST-TMAFL 397

  Fly   403 AMGSMF-----SGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIGAWRIIF 462
            .:.|:|     ||.|.|.:||||.:||.|..|....:.|.|.:.|...||....:...| ||.:|
  Rat   398 VLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFG-WRNVF 461

  Fly   463 GVTIVLFALEFLVFVFLGSGSEQPWNKAGT 492
            .:...:..:..|.::..|....|.|.|..|
  Rat   462 LLAAAIDVVGLLFYLIFGRAEVQDWAKEPT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	145/480 (30%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	118/385 (31%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	140/467 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910