Protein Alignment MFS3 and SLC17A7

DIOPT Version :10

• Sequence 1: NP_608572.1
• Gene: MFS3 / 33292
• FlyBaseID: FBgn0031307
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 161/522 - (30%)
• Similarity: 265/522 - (50%)
• Gaps: 67/522 - (12%)

  Fly    16 VPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVE 80
            :|.||::|::..:|..|.:|::.||.||:|:|||::.  .|     .|||  |::..|.
Human    59 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNST--TH-----RGGH--VVVQKAQ------ 108

  Fly    81 ECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAIN 145
                               |.|.....|.:...:||||:|:|||...:.:.|:|..|..|::...
Human   109 -------------------FSWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVAT 154

  Fly   146 VVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGTA 210
            ....:|.|....:|||.:|.:|:|:|:..|.::||.|.:.:.||||.||..::|..:.|:.||..
Human   155 STLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAV 219

  Fly   211 LSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSLGTEQKT 275
            :::.||||.....||.|||||.|:....|.|.|:::..::|.....||.|||:.|..::|...|.
Human   220 VAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKL 284

  Fly   276 EHHP----AVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVASNAALSALPY 336
             .:|    :.||.:.|||:|.:||::|:.|.::.:|:.||..|.|.::|..|.::....:||||:
Human   285 -MNPLTKFSTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPH 348

  Fly   337 FPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVS----VM 397
            ..|.|.....|::.|.|:::..::||..||...  |... |:...:|..:|..|.:.|:    |:
Human   349 LVMTIIVPIGGQIADFLRSRRIMSTTNVRKLMN--CGGF-GMEATLLLVVGYSHSKGVAISFLVL 410

  Fly   398 SVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIGAWRIIF 462
            :||.  .|...|||..||:||||.:|..|:.::|...||.|:|.|:.||.:|| ::....|:.:|
Human   411 AVGF--SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTK-HKTREEWQYVF 472

  Fly   463 GVTIVLFALEFLVFVFLGSGSEQPWNK-----------------AGTPKDPEAKDEKTPLKELPT 510
            .:..::.....:.:....||.:|||.:                 ||: .|.|.:||..|....|.
Human   473 LIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGS-DDSEMEDEAEPPGAPPA 536

  Fly   511 KP 512
            .|
Human   537 PP 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	MFS_SLC17	23..480	CDD:340876	144/464 (31%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	144/464 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		10/43 (23%)