DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and CG7091

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	133/514 - (25%)
Similarity:	220/514 - (42%)	Gaps:	70/514 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLGSIGM--AIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVEECNPPG 86
            |:||:.:  ||...|...|..||..|:....:|             :::.......:|     |.
  Fly    22 LVGSVRLTYAICAFLATCLHAAMRNMLGMIILK-------------MVMPRPEDALVV-----PA 68

  Fly    87 GAS-----NVTA----------------KVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAE 130
            |.|     |||:                :.:.|...|:...:.|....|::||:||.....::|:
  Fly    69 GLSRLTEGNVTSTGRCGSPRVVFNPQIQETQSGDLPWTRNQELTFPGVYYYGYVVSISLSGYLAD 133

  Fly   131 NFSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERM 195
            ..|:|.:.:.|:....|..:|.|......:...::..|:.|:..|...|||:.:..:||.||||.
  Fly   134 RCSSKRLFIVSLIFEAVAYILLPAMAHSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTERT 198

  Fly   196 VMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLE 260
            .:.:..|.|...|:.|...:|...| .:|||..|||:|.:...:.:....||.|...:...||.|
  Fly   199 ALLSFAYSGLLMGSMLVYPVASYLS-NFGWELSFYVVGGVGLSFGIACCFLVYDTVEQHPRISNE 262

  Fly   261 ERQMI---TSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEI---PFYMKQ 319
            |...:   .|.||  |:.:....:||..:..:.|.:|.::.|.   |..|.||:.:   |.:|::
  Fly   263 EVDYLRQGKSQLG--QQRQPVVTIPWKSLLAAPPVYAFILTHM---FHTYTFLVIVQLMPRFMRE 322

  Fly   320 VLKFNVASNAALSALPYFPMIIFSI-CLGKLLDSLQAKGKI--TTTVARKTATSICTLIPGVCLL 381
            .::|::.....|||.||...|...: |   :|.....:.::  .....|:....||:::....:.
  Fly   323 AMEFDLREVGFLSAAPYLGGICSKVMC---ILGGSYVERRVGPDQNCVRRMLYGICSILTTSLIG 384

  Fly   382 VLCYIGCRHYEAVSVMSVGIVAMGSM-FSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVP-LF 444
            |:....|.....|.||...::|...| |||:....:..||:|||.|..|.|..|.|.|.:.| |.
  Fly   385 VIILANCDDKILVLVMFAFMMATTDMGFSGYWPTLLYFAPSFAGLLSGLANGMAHLSGFLAPHLV 449

  Fly   445 VGFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKDPEAKDEKT 503
            ...|..|:::  .|.::....||...:..|||.|..|.:.|||       ||.::.|||
  Fly   450 AALVHTGSKD--EWNVVLMTLIVFNTMAMLVFAFCSSTNLQPW-------DPRSRMEKT 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	128/498 (26%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	104/389 (27%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	115/438 (26%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	102/377 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970