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Protein Alignment MFS3 and SLC17A5

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001369562.1	Gene:	SLC17A5 / 26503	HGNCID:	10933	Length:	533	Species:	Homo sapiens

Alignment Length:	465	Identity:	173/465 - (37%)
Similarity:	251/465 - (53%)	Gaps:	32/465 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TDEVP-AKGSILGKLVP----ARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGG 61
            ||..| ..|:...:..|    |||.||:|...|..|||.|:||||||:|.||:
Human    17 TDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVD------------ 69

  Fly    62 HGGHGSVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLA 126
               ..:.:..|.:..:..|...|.....|.|.|    .:.|....||.:|..:|:||:::|||..
Human    70 ---SNTTLEDNRTSKACPEHSAPIKVHHNQTGK----KYQWDAETQGWILGSFFYGYIITQIPGG 127

  Fly   127 HVAENFSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPP 191
            :||.....|.::.|.:....|.||.||:..:|..|.||::|.|||:|.|.:|||||.|.:|||||
Human   128 YVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPP 192

  Fly   192 TERMVMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRF 256
            .||..:.:|.|.|...||.:|:.|:|:......|..|||..|.:...|.|||:.||.|.|.|.:.
Human   193 LERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKR 257

  Fly   257 ISLEERQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVL 321
            ||..|::.|.|||..:..::  .:|||..:..|:|.|||::||...|:.:|..|..:|.|||::|
Human   258 ISHYEKEYILSSLRNQLSSQ--KSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEIL 320

  Fly   322 KFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYI 386
            :|||..|..||:|||....:..|..|:..|:|:||...:|...|:..:.|..:.|.|.|:...:|
Human   321 RFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFI 385

  Fly   387 GCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVT-- 449
            ||.:..||:.:::.....|...|||..||:||||::||.|:.:|||.||:||:|.|:....:|
Human   386 GCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPD 450

  Fly   450 KGNQNIGAWR 459
            .|.|    ||
Human   451 AGVQ----WR 456

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.