DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	506	Identity:	94/506 - (18%)
Similarity:	169/506 - (33%)	Gaps:	161/506 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSA 134
            :.||....|.|:....|...|:.|.|                  ::..:::.::|...:.:....
pombe    77 IGNAKVAGLPEDLKLKGDQFNIIASV------------------FYVTFILFEMPTTLLMKKVQP 123

  Fly   135 KWVMLFSVAINVVCTLLTPVFTEL--HYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVM 197
            |.::.|.    |:...||.:||..  ::|||:..|::.|......||.:.:.:
pombe   124 KRMLAFI----VISYSLTTIFTGFCHNFGGLLAARLVLGFCEAGLFPCLALYL------------ 172

  Fly   198 STIIYVGTS---------AGTALSILLAGVCS------------AQWGWESVFYVMGALSCIWML 241
             |:||....         |.:|||....|:.:            |.|.|  :|.:.|.:..:..:
pombe   173 -TMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRW--LFIIEGLIGFVCGV 234

  Fly   242 LWVILVQDNPNKQRFISLEERQMITS---SLGTEQKTEHHPAVPWGKV---FTSVPFWAILIAH- 299
            ....::.::..|..|:|...::|:..   ....:.:..|   ..|..|   ||....:...::.
pombe   235 AVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAH---FDWKGVKSAFTDFKVYLYALSEF 296

  Fly   300 ---TCSNFGWYMFL----------------IEIPFYMKQVLKFNVASNAALSALPYFPMIIFSIC 345
               ||. :|:..||                :.||.|:             |.|..|       |.
pombe   297 GQDTCL-YGFSTFLPAIISGMGYTSLSVQYMTIPVYI-------------LGAATY-------IA 340

  Fly   346 LGKLLDSLQAKGKITTTVARKTATSICTLIP--GVCLLVLC-------YIGCRHYEAVSVMSVGI 401
            ...|.|....:|.|..         |..:.|  |..||:.|       |..|      .:.|||:
pombe   341 ASFLSDRFHHRGIILI---------IGNIFPIVGYILLLACQNNKSVLYFAC------YLCSVGV 390

  Fly   402 VAMGSMFSGFLSNHIDIAPNF-----AGTLVALTNTAATLPGIVV---PLFV-GFVTKGNQNIGA 457
            .....:...:||  .:|||::     ....:|:.|::..|.|.:.   |.:: |.:|.
pombe   391 YTGAGLNVTWLS--ANIAPHYKRATAISLQLAIANSSGILAGQIYRYPPKYIAGHLTS------- 446

  Fly   458 WRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGT------PKDPEAKDEK 502
             .|...::.||..:.........|..::....:.|      |||.  ||.:
pombe   447 -LIAIFISTVLHVVNIFFLKHQNSKKQKSLASSSTIDLSEQPKDD--KDAR 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	88/485 (18%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	79/445 (18%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	85/463 (18%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	81/435 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050