DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and SPCPB1C11.03

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001342988.1	Gene:	SPCPB1C11.03 / 2539453	PomBaseID:	SPCPB1C11.03	Length:	570	Species:	Schizosaccharomyces pombe

Alignment Length:	502	Identity:	101/502 - (20%)
Similarity:	167/502 - (33%)	Gaps:	147/502 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVEECNP 84
            |:|.:||.:.|.:..| |..||.:.:                              :.|.::.:.
pombe   101 YLLLMLGFLDMMLFIG-KATLSYSTI------------------------------LGLFDDVHI 134

  Fly    85 PGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFS-AKWVMLFSVAINVVC 148
            .....|                  .|.:.::.||:|.|.|..::.:.|. .|:|.|.:.:.:|:.
pombe   135 TSNQYN------------------NLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIV 181

  Fly   149 TLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVG-TSAGTALS 212
            .|....:   :|||||.:|...|.......|||...:..:....|:..:..:.::. .|.|....
pombe   182 FLHCCAY---NYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVFWISCLSCGIPAG 243

  Fly   213 ILLAG---VCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSL----- 269
            .:..|   |..:...|:....:.|.::....:.......|||:|.||::.||:......:
pombe   244 FIAYGLEFVTKSIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTR 308

  Fly   270 -GTEQK--TEHH------PAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNV 325
             |.|.|  .:|.      ..:.|  :||...|..:|    .:|..:...||        ....||
pombe   309 GGIENKIFKKHQFIEALKDPITW--LFTFAAFTLML----SNNLAYQQNLI--------FTSLNV 359

  Fly   326 ASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRH 390
            :.                  |...|..:...|  ..||:...||....|||....
pombe   360 SD------------------LNSTLVGVALAG--YNTVSAIIATFAMYLIPNQSA---------- 394

  Fly   391 YEAVSVMSVGIVAMGSMFSGF-LSNHID------IAPNFAGT-LVALTNTAATLPGIVVPLFVGF 447
            |.|:..|...|.. |..|... .||.|.      ||.:|..| ::||..|.||..|....|
pombe   395 YHAMFWMLPSITG-GIAFVALPWSNRIGELATMIIASDFGITYIIALGWTTATSTGYTKKL---- 454

  Fly   448 VTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPK 494
             |:|        ::|   :|.:|:..::       |.|.|.....|:
pombe   455 -TRG--------LMF---MVGYAIANII-------SPQLWQSRDAPR 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	100/495 (20%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	86/405 (21%)
SPCPB1C11.03	NP_001342988.1	UhpC	102..494	CDD:332119	100/501 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050