DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and slc-17.6

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_490947.2	Gene:	slc-17.6 / 171781	WormBaseID:	WBGene00017398	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	499	Identity:	112/499 - (22%)
Similarity:	217/499 - (43%)	Gaps:	66/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LGKLVPARYVLALLGSIGMAIVYGL-KVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQ 75
            |..|...|:..|||.| ...:|:|| :....:|||.:|.      .|:|..|
Worm    19 LWTLQSIRFQTALLIS-AACVVFGLMRTCFGMAMVDIVR------SGNGTFH------------- 63

  Fly    76 VSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLF 140
                                .|...:||...|..:.:.::.|..::..|...:|:....|.::.|
Worm    64 --------------------PDLHMEWSGDEQANIHTSFYIGAFIAVFPSEFLAKKLGPKNLLSF 108

  Fly   141 SVAINVVCTLLTPVFTELH---YGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIY 202
            ::.:|:..:|||| |:.::   |..:..:|::.|.|.|...||..|:|:||.|.:|:.....|..
Worm   109 ALLLNIFGSLLTP-FSAIYLRSYFPVAAIRLIMGFGYGFVIPAGSVLISSWFPLSEKSTAMAIFT 172

  Fly   203 VGTSAGTALSILL-AGVCSAQW--GWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQM 264
            .|...|.|:|:.| |.:|...:  ||..||.|.|.:..:::::|.:.:.|.|.:.::|:..|
Worm   173 TGNQIGIAVSMFLTAKLCQLHFFEGWPLVFIVYGLIGAVFLVIWHVRLADKPRESKYITATE--- 234

  Fly   265 ITSSLGTEQKTEHHP----AVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNV 325
            :|...|.:|:.....    |.|:.|:..:....||.......:|.....:..:|.|.:...|.|:
Worm   235 LTYIKGGKQRRNRAETIVRATPYMKIILNGCVCAICACSFAQSFVLVALVTYLPKYNQIAFKMNL 299

  Fly   326 ASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRH 390
            ..|...|:||:|..:|..:....:.|.::.: |:..|...|.:.:|.:....:.:::..|   ..
Worm   300 THNGIWSSLPFFIQMITKLLFAIIADKVKQR-KVNATAVTKVSNAIASFASAIFIVIAAY---GP 360

  Fly   391 YEAVSVMSVGIVAMGSMFS----GFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKG 451
            :::..::.:.|:...:.||    |:.::.:.:||.|...:.:.....|.:...:.|:.:|.:| .
Worm   361 FDSAELVQLSIIVSMAAFSAYVPGYNTSIVTVAPQFTAFISSYAQLYAQIASTLAPIVIGRIT-S 424

  Fly   452 NQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKD 495
            :..|..|:..|.....:.|:..|:|...|.|..:||.:  ||.:
Worm   425 HGTIYEWKCAFYSLAGVLAVTGLIFQIFGHGRTEPWGE--TPSN 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	108/484 (22%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	88/392 (22%)
slc-17.6	NP_490947.2	MFS	30..453	CDD:391944	103/471 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010