Protein Alignment MFS3 and SLC17A3

DIOPT Version :9

• Sequence 1: NP_608572.1
• Gene: MFS3 / 33292
• FlyBaseID: FBgn0031307
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 132/495 - (26%)
• Similarity: 227/495 - (45%)
• Gaps: 34/495 - (6%)

  Fly     3 DE--VPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGH 65
            ||  :|.|   :..|..|||.:||:............|.:::.||||||.|:.::.
Human    23 DETLIPRK---VPSLCSARYGIALVLHFCNFTTIAQNVIMNITMVAMVNSTSPQSQ--------- 75

  Fly    66 GSVILSNASQVSLVEECNPPGGAS----NVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLA 126
                |:::|:|..|:..   ||.|    ::.||..  .:|||..:||.:.....:|.:::..|..
Human    76 ----LNDSSEVLPVDSF---GGLSKAPKSLPAKAP--VYDWSPQIQGIIFGAVGYGGILTMAPSG 131

  Fly   127 HVAENFSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPP 191
            ::|.....|.|:..|:......||..|:.|:.....||:.|:::|:...:.......:...|.||
Human   132 YLAGRVGTKRVVGISLFATSFLTLCIPLATDFGIVLLIVTRIVQGLSQSSILGGQFAIWEKWGPP 196

  Fly   192 TERMVMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRF 256
            .||..:.:|...|...|...:||:.|..|...||..|||:.|.:.|:..|||.:::.|:|....:
Human   197 QERSRLCSIALSGMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPW 261

  Fly   257 ISLEERQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYM--FLIEIPFYMKQ 319
            ||..|::.|.|||..:..:...| :|...:..|:|.|:|.:.  |.:..|.:  .::.||.|:..
Human   262 ISTSEKEYIISSLKQQVGSSKQP-LPIKAMLRSLPIWSICLG--CFSHQWLVSTMVVYIPTYISS 323

  Fly   320 VLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLC 384
            |...|:..|..|||||:....:..:..|.|.|.|..| |......||.||.:.:|.....::.|.
Human   324 VYHVNIRDNGLLSALPFIVAWVIGMVGGYLADFLLTK-KFRLITVRKIATILGSLPSSALIVSLP 387

  Fly   385 YIGCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVT 449
            |:...:..|.:::::.........||...|.:||||.::..|:..:...:::..::||...||:.
Human   388 YLNSGYITATALLTLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLL 452

  Fly   450 KGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNK 489
            ..:...| ||.:|.:...:..|..|.::..|....|.|.|
Human   453 SQDPEFG-WRNVFFLLFAVNLLGLLFYLIFGEADVQEWAK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	125/475 (26%)
		MFS	100..479	CDD:119392	101/380 (27%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	132/495 (27%)
		MFS	98..481	CDD:119392	103/389 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820