Protein Alignment MFS3 and SLC17A4

DIOPT Version :9

• Sequence 1: NP_608572.1
• Gene: MFS3 / 33292
• FlyBaseID: FBgn0031307
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 141/496 - (28%)
• Similarity: 227/496 - (45%)
• Gaps: 33/496 - (6%)

  Fly     3 DEVPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGS 67
            :|...||     ....|:.|||:..:....:|..::|||:|:.||||:||..:.
Human    25 EECSRKG-----FCSVRHGLALILQLCNFSIYTQQMNLSIAIPAMVNNTAPPSQ----------- 73

  Fly    68 VILSNASQVSLVEECNPPGGASNVTA---KVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVA 129
               .||   |.........|..|.|.   |.....:|||..:||.:||...:|..::.||..:||
Human    74 ---PNA---STERPSTDSQGYWNETLKEFKAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVA 132

  Fly   130 ENFSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTER 194
            ..|.||:|:...:.|:...||..|:........||::|:::|:.........:.:...||||.||
Human   133 GIFGAKYVVGAGLFISSFLTLFIPLAANAGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLER 197

  Fly   195 MVMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISL 259
            ..::||...|:..|:.:.:|..|:.....||..|||:.|.:.|....||..|:.|:|....|||.
Human   198 SQLTTIAGSGSMLGSFIVLLAGGLLCQTIGWPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISA 262

  Fly   260 EERQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFN 324
            .|::.|..|| .:|......::|...:..|:|.||||:::.|..:.:|..:...|.|:..||:.|
Human   263 GEKRYIVCSL-AQQDCSPGWSLPIRAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQAN 326

  Fly   325 VASNAALSALPYFPMIIFSICL---GKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYI 386
            :..:..|||||:   ::..||:   |.|.|.|.::..:.....||..|:|..|.|.|.|:.|.::
Human   327 LRDSGILSALPF---VVGCICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWV 388

  Fly   387 GCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKG 451
            ...|...::.:.:.........||.|.|.:||||.:.|.|..|....|.:.|.:.|...||....
Human   389 RSSHSMTMTFLVLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAGFFISQ 453

  Fly   452 NQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGT 492
            :...| ||.:|.::..:.....:.::..|....|.|.|..|
Human   454 DSEFG-WRNVFLLSAAVNISGLVFYLIFGRADVQDWAKEQT 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	136/475 (29%)
		MFS	100..479	CDD:119392	111/381 (29%)
SLC17A4	NP_005486.1	UhpC	30..491	CDD:332119	138/487 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810