DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS3 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	507	Identity:	164/507 - (32%)
Similarity:	256/507 - (50%)	Gaps:	59/507 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VPARYVLALLGSIGMAIVYGLKVNLSVAMVAMV-NHTAIKAHGDGGGHGGHGSVILSNASQVSLV 79
            :|.||::|:|..:|..|.:|::.||.||:|:|| |||..:   ||..:
Zfish    59 LPRRYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYR---DGKPY----------------- 103

  Fly    80 EECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAI 144
                           :....|.|.....|.:...:||||:|:|||...:.:.|:|..|..|:|..
Zfish   104 ---------------IVKAQFSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVS 153

  Fly   145 NVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGT 209
            ..:..::.|....:|:|.:||:|:|:|:..|.|:||.|.:.|.||||.||..::|..:.|:.||.
Zfish   154 TSILNMMIPTAARMHFGCVILVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGA 218

  Fly   210 ALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSLGTEQK 274
            .:::.||||.....||.|||||.|:....|.|.|:::..::|.....|:.|||:.|..::| |..
Zfish   219 VIAMPLAGVLVQYSGWSSVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAIG-ESA 282

  Fly   275 TEHHPA----VPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVASNAALSALP 335
            ...:|.    .||.:.|||:|.:||::|:.|.::.:|:.||..|.|.::|.||.::....|||||
Zfish   283 GLVNPLTKFNTPWRQFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALP 347

  Fly   336 YFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVS----V 396
            :..|.|.....|:|.|.|:....:|||..||........:....|||   :|..|.:.|:    |
Zfish   348 HLVMTIVVPIGGQLADYLRTHNLMTTTNVRKLMNCGGFGLEATFLLV---VGFSHTKGVAISFLV 409

  Fly   397 MSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIGAWRII 461
            ::||.  .|...|||..||:||||.:|..|:.::|...||.|:|.||.||.:|| |:....|:.:
Zfish   410 LAVGF--SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTK-NKTREEWQYV 471

  Fly   462 FGVTIVLFALEFLVFVFLGSGSEQPW--------NKAGTPKDPEAKDEKTPL 505
            |.:..::.....:.:....||.:|||        .|.|...:.|..||...|
Zfish   472 FLIASLVHYGGVIFYGLFASGEKQPWAEPENTSEEKCGILGEDELADETEEL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	157/486 (32%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	133/386 (34%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830