Protein Alignment HSPD1 and CCT7

DIOPT Version :10

• Sequence 1: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_649835.1
• Gene: CCT7 / 41054
• FlyBaseID: FBgn0037632
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 590
• Identity: 131/590 - (22%)
• Similarity: 231/590 - (39%)
• Gaps: 140/590 - (23%)

Human    47 LADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGD 111
            :.|||..|:||:|...:|..:.|...::.||.|:.|.:::    .:..||.:.|:|.:.:.|.||
  Fly    31 IVDAVRTTLGPRGMDKLIVDAHGKATISNDGATIMKLLEI----IHPAAKTLVDIAKSQDAEVGD 91

Human   112 GTTTATVLARSIAKEGFEKISKGANP----VEIRRGVMLAVDAV---IAELKKQSKPVTTPEEIA 169
            |||:..:||....|:....:.:|.:|    ..||:.:.|.::.:   ..::.:|||  .....:.
  Fly    92 GTTSVVLLAGEFLKQVKPFVEEGVHPRVIIKAIRKALQLCMEKINEMAVQIVEQSK--DQQRALL 154

Human   170 QVATISANGDKEI-------GNIISDA---------MKKVGRKGVITVKDGKTLNDELEIIEGMK 218
            :....:|...|.|       ..|:.||         :..:|.|.|    .|.:| :|.:::.|:.
  Fly   155 EKCAATAMSSKLIHQQKDFFSRIVVDAVLSLDELLPLNMIGIKKV----TGGSL-EESQLVSGVA 214

Human   219 FDRGYISPYF--------------INTSKGQKCEFQDAYVLLSEKKISSIQSIVPA------LEI 263
            |.:.:....|              :|.....|.|..:|.:.:.  .:...|.:|.|      .::
  Fly   215 FKKTFSYAGFEMAPKSYDNCKIALLNIELELKAERDNAEIRVD--NVKEYQKVVDAEWQILYNKL 277

Human   264 ANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDN--------RKNQLKDMAIAT 320
            |..|             |:.:.:||::|.:|    .|....|.|.        .:..||....|.
  Fly   278 AKIH-------------ESGANVVLSKLPIG----DVATQYFADRDIFCAGRVPEEDLKRTMKAC 325

Human   321 GGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEY 385
            ||||.    .|.|  |::|:.||                              :.|..:......
  Fly   326 GGAVM----TTAN--DIKPNVLG------------------------------LCEHFEERQVGG 354

Human   386 EKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVE-EGIVLGGGCALLRCIP 449
            |:..|.:..........:|:.|....:|..|:.  :.||:...|..:: :.:|.|||...:....
  Fly   355 ERFNLFQGCPNAKTSTLILRGGAEQFLEETERS--LHDAIMIVRRTIKHDSVVAGGGAIEMELSK 417

Human   450 ALD--SLTPANEDQKI------GIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE----VG 502
            .|.  |.|.|.::|.:      |:|||.|.|       ..|||.:.:.|:.|:.|..::    .|
  Fly   418 LLRDYSRTIAGKEQLLIAAIAKGLEIIPRQL-------CDNAGFDATNILNKLRQKHAQGGQWYG 475

Human   503 YDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGG 567
            .|....|..:..|:.:.:|:.:...||..||..|.::.:.:..: :.||..:.|..|...|||.|
  Fly   476 VDINKEDISDNYEQCVWEPSIIKINALTAAAEAACMILSVDETI-KSPKAGEPPMAGGGMGMGRG 539

Human   568 MGGGM 572
            ||..|
  Fly   540 MGRPM 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	120/564 (21%)
CCT7	NP_649835.1	TCP1_eta	4..524	CDD:239456	121/568 (21%)