Protein Alignment CG14339 and cfap70

DIOPT Version :10

• Sequence 1: NP_608566.1
• Gene: CG14339 / 33286
• FlyBaseID: FBgn0031301
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_002940644.2
• Gene: cfap70 / 100379775
• XenbaseID: XB-GENE-994711
• Length: 1113
• Species: Xenopus tropicalis
• Alignment Length: 1211
• Identity: 219/1211 - (18%)
• Similarity: 373/1211 - (30%)
• Gaps: 463/1211 - (38%)

  Fly    74 EFHSKPTFTLIFQQDNVDRINHAADNPLLVQLYMRVLPPRRIVQVEYEMLEEEQEGDLEADSDSD 138
            |||...:|.:  ..|....::..|..|:::.| :.:||.           |::|:.:
 Frog    62 EFHFTSSFDV--SPDGPHSLDDVAHKPVILTL-IEILPK-----------EKKQKEE-------- 104

  Fly   139 LTMSTTIATTLLDDDAFEARETVKLELLCVGYLDVIKLFGHRRSMICEELFLYPMPDVPNEMRST 203
                                :||.|....|..|.::|  |.....:  .|.|:|:...|.| .:.
 Frog   105 --------------------KTVVLGQAAVDLLPLLK--GESNFKV--TLPLHPVTGSPLE-SAQ 144

  Fly   204 IHTEWHLYTLLPIAKKLTFT------NMAFVTFESIYCLKD---------EYVLDLETLWVRVSF 253
            :.|:..|...:.:.:.|...      |:..||.|::||..:         .||:.|:
 Frog   145 LDTKPSLEVAVSVPEPLLSDAQINNGNILRVTVEAVYCAPESWNTTGPAYNYVMSLQ-------- 201

  Fly   254 RSRMP--GDRNESLIPLCEFGNLERKIICMQDNHHVFESFRRSVKPWNVTGL--KSAMEVQRHRL 314
               ||  |:...||:    |.|...|.      ....|...|. |.|.|||:  .||..:....:
 Frog   202 ---MPPAGELPHSLV----FSNGTLKA------GGEAEPVPRP-KKWPVTGMAATSAQNIPDSFI 252

  Fly   315 FSELFHSENLTPDFEEIDPAMDEALVCNS------------FHRFILTQSMADILSFAITCQQYV 367
            |...:..||     .|::...|:....::            ..|::...::..|......|:.:
 Frog   253 FGGPYEEEN-----GELNRKEDKEFRADAETLKKRVTWDTERRRYLDPSALLSIQKQIAECRYW- 311

  Fly   368 LAVEVFQTFGAA-----KPQKVFQGVLDPSI------------MAYPGVQNMRFAVQL------- 408
             .||:.:....|     ||.||.:|..|..|            :.||||:::|.|.::
 Frog   312 -PVEIMRAPTVAPSTKGKPGKVDKGDEDGQISFHGVAYVNMVPLLYPGVKHLRGAFRIYPYQDAE 375

  Fly   409 ------------------------------------------------------DYLGK----LK 415
                                                                  :|..|    :|
 Frog   376 VLEKTKCQSSALRDVARQTGLQSRVGFAPAGVNSPHGKQGPSRIVREDKVTKDKEYTRKPSAPMK 440

  Fly   416 PKKIMSTFNLKSMERAKTLP------------TFAIIKLCLLAPIGEIYKELKVFRESFIRQNRL 468
            |....|.....:...|:|.|            |:.|::|.|..|:  :.|.|   .|....:.|.
 Frog   441 PLDTASEAETIAPVPAQTAPQNVEGQQYTESGTYVILELSLEKPL--VPKRL---AEEIDLRVRE 500

  Fly   469 LFCDRPY----SSINAMSLAEIQMECYARFDKFIRD-CISFIIDKKVMK--------LEDKK--- 517
            |...||.    |:..|.::.:...:..:..|..:.: |..|  .:|..:        ||::|
 Frog   501 LIPSRPQLPRRSAGAAKAVTDYHNQITSITDSILEEYCELF--GRKAAEAEELDHQALEEQKCQL 563

  Fly   518 --------QHFCCAVQNLTNILMKVVGSVYNTRT----PTNTSVDFANLCAFAYNELE------- 563
                    ::|....| |.:.::|:|...|...|    |.......:.|..:..:::.
 Frog   564 NYELNCTGKYFAFKEQ-LKHAVVKIVREKYLKTTAFEDPEQLQAFLSELYVYLVDQMHIALNKTL 627

  Fly   564 --------PRVHTVVEQI-----ENEGFDSYTISKQIQNERI----------IDYLNTIKLLL-- 603
                    |...|..||:     |.|....:.::.....||:          :|| .:.:||:
 Frog   628 FDDRGEPAPPPMTDTEQLLRFAREAEITGDFDLANTFYQERLARDRQCVDHWLDY-GSFQLLIGD 691

  Fly   604 -----------MVNDENH-------------------AHLLMEKAITEYPSNERFW--------- 629
                       :|...:|                   |.:..|.|....||:...|
 Frog   692 YIKAQECFHEAVVLRRDHVPSLLLSGIAAATLDHCKDAEVFFEDATCTDPSSTLAWTLLGLLYEM 756

  Fly   630 ----FYMVIAYMERGELEKAKVYFKKNHLADTHDYFAGWIKL-----------------YINYVD 673
                ..|.:|:.|.|:|..||       .|........|.|.                 .::...
 Frog   757 QGNDIRMEMAFSEAGKLRLAK-------CAQERAVALSWAKPAGGTNSKSALGNASEKGTLSKGA 814

  Fly   674 TRNNPETAPDCTECLLRSITNYAERYPRQQDAWILLYCYYKRFNYEPGCAFALWRFGDQHGHCRL 738
            |....||.|........|:.......|.::.|                   :|.|        |.
 Frog   815 TEGPHETTPASHRAESPSVNISLSGRPAEEKA-------------------SLTR--------RA 852

  Fly   739 SSSSNAPHSLWGLYVNLNITIPTSRGT--------------------MFLEVFRTFARLGLYEFA 783
            |.||....|             |..||                    :|:|..:...|:...:|.
 Frog   853 SVSSLRSKS-------------TKAGTHKEVTTRASSEPEAQPEAISIFMEAAQFLTRVNALQFV 904

  Fly   784 QVVIAAVL--PLASDADRYMLQ-TQLDMMLNQLDENFVPLSFEFEEGEEGDYSAAMNAQIN---- 841
            |..:|..|  |......||.|. .|:.:|..:|              |:...:....:|||
 Frog   905 QRALAHELLCPDGGPTCRYQLMCAQMHLMRKEL--------------EKAQQNLQEASQINHQNP 955

  Fly   842 ------GNVEFQRGNLEEAALYYESALTLPPPEVNERDFFEVSRLRLGYISYELGNYNK------ 894
                  |::.|..|...||...||..|:|    |::........||||.|..:...|.|
 Frog   956 DVWALKGHLNFLSGRKSEAKGCYEHTLSL----VSDASDMHPVYLRLGSIYLDEEEYEKAKKTYL 1016

  Fly   895 --------CIEALSFPFAGQLLSIVANYMIGKSYYKLDLLDLALESFANATHMDTHVPNVWGFLA 951
                    |:..|.               .|.:.|:|:.::.|.::.:.|..::.:...|||:|.
 Frog  1017 LACKQSPTCLTWLG---------------AGIACYRLEEMEEAEDALSEANALNNNNAEVWGYLT 1066

  Fly   952 LINLRLGENYKAIECWKYAKIEPNYPIDDMM-----IYEEL 987
            |:.|:.|...:|.:.:||.: :.|...:|::     :.|||
 Frog  1067 LVCLKTGRQLEAEQSYKYTR-KLNLQKEDLLTEIHSLQEEL 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14339	NP_608566.1	NrfG	<601..651	CDD:443378	17/94 (18%)
		TPR	831..>977	CDD:440225	38/169 (22%)
		TPR repeat	868..910	CDD:276809	10/55 (18%)
		TPR repeat	911..936	CDD:276809	4/24 (17%)
		TPR repeat	944..970	CDD:276809	9/25 (36%)
cfap70	XP_002940644.2	Spy	602..>774	CDD:443119	25/172 (15%)
		TPR repeat	643..670	CDD:276809	6/26 (23%)
		TPR repeat	679..704	CDD:276809	4/25 (16%)
		TPR repeat	709..739	CDD:276809	4/29 (14%)
		TPR repeat	744..770	CDD:276809	3/25 (12%)
		TPR	928..>1096	CDD:440225	43/201 (21%)
		TPR repeat	954..984	CDD:276809	8/29 (28%)
		TPR repeat	992..1020	CDD:276809	7/27 (26%)
		TPR repeat	1026..1050	CDD:276809	5/38 (13%)
		TPR repeat	1059..1083	CDD:276809	8/23 (35%)