Protein Alignment CG4629 and SKS1

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_015299.1
• Gene: SKS1 / 856081
• SGDID: S000005947
• Length: 502
• Species: Saccharomyces cerevisiae
• Alignment Length: 566
• Identity: 119/566 - (21%)
• Similarity: 195/566 - (34%)
• Gaps: 173/566 - (30%)

  Fly    66 YRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVV----DLD----RAGL------------------ 104
            :|....||.|.:..|...|..||..:.|:|.|    .:|    :.||
Yeast    10 FRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGLNNNSQVARTTLLQTQLYH 74

  Fly   105 --------------DAKALRMLSS----------EIA-TLECVHHPNILRLFEVVETLGRVYLVT 144
                          |..::..|:.          ||| .|....|.||:::.:|:|:....::|.
Yeast    75 FFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVM 139

  Fly   145 EWIRGGELYNHITQGGPLREIHAAPLLK----QLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLK 205
            ::. ..:|:..|......  ::...|:|    ||..|:.|.|.||..|.|||.|||||...|...
Yeast   140 DYY-DRDLFTSIVDDKHF--VNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAY 201

  Fly   206 LADFGFSTQLINGANQKLDTFC-GSPPYAAPE------------LFSDDHYIGAPV---DVWALG 254
            |.|||.||:    :.......| ||..|.|||            :..|:.....|.   |:|:||
Yeast   202 LCDFGLSTK----SKYLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDTGDIWSLG 262

  Fly   255 ILLYFMV-VGNMPFRAPTIPGLKA---------------AILKGDYLLPGQLSLPCIRLIQRILI 303
            |:|..:. :.|        |.|||               .:||  .:||  :|.....::.:||.
Yeast   263 IILINLTCIRN--------PWLKAHQKEDNTFQHFANDNNVLK--KILP--ISDELFTVLTKILQ 315

  Fly   304 HIPAQRPTIDDMLN-----SQFV------TCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLR 357
            ..|..|..:..:::     :.|.      ..|.||:::....|      ::....::...||
Yeast   316 LNPYTRIDMKTLMSEVSSLTSFTREGPLSQVPILSSEVYMTHI------IRNENLFLSDLSH--- 371

  Fly   358 KSASLRDRYAEVVKKPAISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTR 422
            .||....:..:..::..:....::|.:..:||               ..|.::.|..|.|
Yeast   372 FSADQEQQQQQQQQQQQVQEQEQEQKQEQIQN---------------QEQAQQQQEEEDA----- 416

  Fly   423 RYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLP-- 485
                             |||..:.:...|.||       :|..|......|....|.|....|
Yeast   417 -----------------EPESDIPSTYNSDGS-------MEKYEYTNNHNNSTFLTSSMDSTPYQ 457

  Fly   486 TNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGPRSDIIGAY 531
            ::.:|:|.....:|:...:...| |..:|..:....||....:..|
Yeast   458 SDIDDVSASKDCKFQQDTLRNRL-LCLQMNFSTLTDGPNEKWLPDY 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	82/346 (24%)
SKS1	NP_015299.1	Protein Kinases, catalytic domain	9..331	CDD:473864	82/339 (24%)