Protein Alignment CG4629 and FRK1

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_015184.1
• Gene: FRK1 / 855962
• SGDID: S000006062
• Length: 865
• Species: Saccharomyces cerevisiae
• Alignment Length: 584
• Identity: 146/584 - (25%)
• Similarity: 232/584 - (39%)
• Gaps: 160/584 - (27%)

  Fly    64 GLYRFCGDIGRGNFSKVKLA-------VHQLTRD---KVAIKVVDLDRAGLDAKALRMLSSEIAT 118
            |.|.....:|.|.|.||||.       ....|.|   :||||::..|....|.:....:..||..
Yeast    39 GPYILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINA 103

  Fly   119 LECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHS 183
            |:.:.||||::|.||::....:.:|.|:..|||.|.:|.:...|:|::|..|..||:..|.::||
Yeast   104 LKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHS 168

  Fly   184 LGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPEL-FSDDHYIGAP 247
            .|.||||:|.||:||...:.|.:.||||..:..: .|:.:.|.||||.|||||| .|.:.|....
Yeast   169 KGLVHRDLKLENLLLDKNENLVITDFGFVNEFCS-RNELMKTSCGSPCYAAPELVISAEPYEARK 232

  Fly   248 VDVWALGILLYFMVVGNMPF-RAPTIPG----------LKAAILK-GDYLLPGQLSLPCIRLIQR 300
            .|:|:.|::||.::.|.:|: ..|..|.          :.:..|| .||:||
Yeast   233 ADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILP------------- 284

  Fly   301 ILIHIPAQRPTIDDMLNSQFVTCPKLSADLMQWEINQHTKPVKRSIF-------WVR-SKSHRLR 357
                ||.      |:|....|:.||...:|.|.:.::..||  .|.|       |.: :.:..:.
Yeast   285 ----IPR------DLLRRMLVSDPKKRINLKQIKKHEWLKP--HSSFLSITPDEWDKLNNTQSVF 337

  Fly   358 KSASLRDRYAEVVKKPAISMNTR-------QQDEMFV--------------QNF----------- 390
            :.|..|.||.   .:|..|.:|.       ::|.:.:              ||.
Yeast   338 RLAKPRRRYG---SRPQSSCSTSSLGSRSDKRDSLVIDSTLITFPAPPQESQNHIITRPASIASD 399

  Fly   391 --LQPIEMGHE-----------LLVPVSSQLKEPQSTEQAKRPTRRY-MFCGSLKKKVTP----- 436
              |.||...:.           |...|::..:...|.||:..|.:.. ...|::...::|
Yeast   400 QRLSPIRRSNRHNRSNSAASVALQAVVNADREYVLSHEQSLSPVQNIRQTTGNMTASLSPPPAIS 464

  Fly   437 -----METEPEKQLANGGQSI------------GSAKINPWNVEVAEDCPLFKNYDAET------ 478
                 :||.|.|:....|.||            .::||.|.|:..:::....||....:
Yeast   465 PGDIIIETTPIKRNTISGSSIVPSLEEESSTTMQTSKIQPNNMASSQNHQYNKNKTQNSLQSAKN 529

  Fly   479 -------------------GSCVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGP 523
                               ||....|.|:..|| :..:..:|:      ...|...:|.|.:.|
Yeast   530 FYRTSSSSHTKPRPTSYHPGSYTTPPYNSNTLS-IYEINEKAK------SSASSQTLNQRDTSP 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	91/279 (33%)
FRK1	NP_015184.1	Protein Kinases, catalytic domain	39..313	CDD:473864	96/297 (32%)