Protein Alignment CG4629 and VHS1

DIOPT Version :9

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_010533.1
• Gene: VHS1 / 851834
• SGDID: S000002655
• Length: 461
• Species: Saccharomyces cerevisiae
• Alignment Length: 559
• Identity: 115/559 - (20%)
• Similarity: 183/559 - (32%)
• Gaps: 208/559 - (37%)

  Fly    62 RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKA------------------ 108
            ||..|.....||.|.:..|..|:...|..:.|||.| :...|:..:|
Yeast     8 RINNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAV-VQSYGVSKEADMGNDKIHKNSVKLQKKL 71

  Fly   109 ----------LRMLSSEIATLECV---------------------HHPNILRLFEVVETLGRVYL 142
                      :|:.|.::.::|.:                     ||.||:.:.||:::....::
Yeast    72 AKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFI 136

  Fly   143 VTEWIRGGELY------NHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSE 201
            |.::. ..:|:      .|....|.|    ...:..|:..|:.:.|..|..|.|||.||:||.:|
Yeast   137 VMDYY-PTDLFTSIVDNRHFVTNGLL----VKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTE 196

  Fly   202 DRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDD----------HYIGAPV-----DVW 251
            |.:.|.|||.||   .....|.:...||..|..||..|.|          |.:|...     |:|
Yeast   197 DNVFLCDFGLST---TSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLW 258

  Fly   252 ALGILLYFMV-VGNMPFRAPTIPGLKA---------------AILKGDYLLPGQLSLPCIRLIQR 300
            :|||:|..:. :.|        |.|||               .|||  .:||  ||.....|:.:
Yeast   259 SLGIILINLTCIRN--------PWLKADKTEDNTYYYFTKDPNILK--QILP--LSDDFYSLLSK 311

  Fly   301 ILIHIPAQRPTIDDMLN-----SQFVTCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSA 360
            ||...|..|.::.:::.     :.|.....||          ...|:.:|::
Yeast   312 ILQVNPKNRMSLQELMKEVSSITSFTNEGPLS----------KVPPLSKSVY------------- 353

  Fly   361 SLRDRYAEVVKKPAISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYM 425
                                       :.|:.|::..:|.|.|.|..                ||
Yeast   354 ---------------------------EKFVSPVDNTNENLSPKSYV----------------YM 375

  Fly   426 FCGSLKKKVT-PMETEPEKQLANG-----GQSIGSAKINPWNVEVAEDCPLFKNYDAETG-SCVM 483
            ......|.:: ...:|.|..:..|     |...||                |...|.:|| ....
Yeast   376 HDSKAAKNLSYTSSSEEEDGIKEGIDDDNGSRSGS----------------FGTLDTDTGLHSSF 424

  Fly   484 LPTNTEDLSQLGALE-----FEARQILAELGLTSEMLIN 517
            ..|:.|..::...:.     ||.:  ..||.::|..|.|
Yeast   425 TSTSCESDNECSKISNKFSLFEKK--FNELRMSSSSLTN 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	81/348 (23%)
		S_TKc	66..321	CDD:214567	80/345 (23%)
VHS1	NP_010533.1	STKc_Pat1_like	11..330	CDD:270895	80/339 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930