Protein Alignment CG4629 and Prkaa2

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_076481.2
• Gene: Prkaa2 / 78975
• RGDID: 620893
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 101/262 - (38%)
• Similarity: 155/262 - (59%)
• Gaps: 14/262 - (5%)

  Fly    60 GR-RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDR-AGLDAKALRMLSSEIATLECV 122
            || :||.|.....:|.|.|.|||:..||||..|||:|:::..: ..||  .:..:..||..|:..
  Rat     9 GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLD--VVGKIKREIQNLKLF 71

  Fly   123 HHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYV 187
            .||:|::|::|:.|....::|.|::.||||:::|.:.|.:.|:.|..|.:|:|.||.:.|....|
  Rat    72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVV 136

  Fly   188 HRDIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWA 252
            |||:|.|||||.::...|:||||.|..:.:|  :.|.|.||||.|||||:.|...|.|..||:|:
  Rat   137 HRDLKPENVLLDAQMNAKIADFGLSNMMSDG--EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199

  Fly   253 LGILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHI----PAQRPTID 313
            .|::||.::.|.:||....:|.|...|..|.:.:|..|:    |.|..:|:|:    |.:|.||.
  Rat   200 CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLN----RSIATLLMHMLQVDPLKRATIK 260

  Fly   314 DM 315
            |:
  Rat   261 DI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	99/258 (38%)
Prkaa2	NP_076481.2	STKc_AMPK_alpha	13..268	CDD:270981	99/258 (38%)
		UBA_AID_AAPK2	285..349	CDD:270587
		AIS. /evidence=ECO:0000250|UniProtKB:Q13131	291..376
		AMPKA2_C	395..550	CDD:213385
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	478..520