Protein Alignment CG4629 and Smok3b

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001034978.1
• Gene: Smok3b / 622474
• MGIID: 3615348
• Length: 504
• Species: Mus musculus
• Alignment Length: 523
• Identity: 143/523 - (27%)
• Similarity: 228/523 - (43%)
• Gaps: 128/523 - (24%)

  Fly    72 IGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVET 136
            ||.|..:.||||.|:||...||:|.:.......:    |:: ||:..|....||||:.|.:|:||
Mouse    34 IGHGGCATVKLAQHRLTGTHVAVKTIRKREYWCN----RVI-SEVELLMMADHPNIISLLQVIET 93

  Fly   137 LGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSE 201
            ..:|||:.|..:|..||.||.:.|.|:|..|..|.||||.|:.:.|:.|.||||:|.:|:::..:
Mouse    94 KKKVYLIMELCKGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKD 158

  Fly   202 DRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMP 266
            .::|:.|||..|::..|  |||:.|||:.|::|||:.....|.|..:|||.||::|||||.|.:|
Mouse   159 GKVKIIDFGLGTKVKPG--QKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVVLYFMVTGKIP 221

  Fly   267 FRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVT--------- 322
            |.|.:|..|...||.|.|.:|.:||.....|:..::...|..|||:.:::...:||
Mouse   222 FDACSIKKLVKRILAGKYSIPSRLSAELQDLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDP 286

  Fly   323 CPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQDEMFV 387
            |             :...|:|.....|::..|...::..:.|           |:..|:.::..
Mouse   287 C-------------EEQTPLKPDPAIVKAMGHIGFQAQDIED-----------SLRQRKFNQTM- 326

  Fly   388 QNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFCGSLKKKVTPM--------------- 437
                            .|..|.:.|..::..||||    ...:...|||.
Mouse   327 ----------------ASYCLLKKQILKECDRPTR----ARPVNPSVTPFPSLVDTATTRLGLRR 371

  Fly   438 -ETEP-------EKQLANGGQSIG----------SAKINPWNVEVAED------------CPLFK 472
             |.||       .:|::..|:|..          |....|.:.....|            |.:|
Mouse   372 RENEPTCPWSSANRQVSVCGKSTSKKRDRRVSWPSVLGRPRHTAPTMDHTRTRTRSVPCICSMF- 435

  Fly   473 NYDAETGSCVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGPRSDIIGAYRIVVNR 537
                    |.:.|.::|:.:| |.....|          ::..:::| ..||. |.|..|::.|.
Mouse   436 --------CTVQPNSSEESTQ-GHTRASA----------ADKPVHSR-GWPRG-IKGWTRMIGNA 479

  Fly   538 LQK 540
            ::|
Mouse   480 MRK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	98/248 (40%)
Smok3b	NP_001034978.1	STKc_AMPK-like	27..275	CDD:270905	98/247 (40%)
		UBA_MARK_Par1	295..334	CDD:270522	7/66 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..421		5/31 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	441..468		6/38 (16%)