Protein Alignment CG4629 and sik1

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001119855.1
• Gene: sik1 / 553465
• ZFINID: ZDB-GENE-030131-9446
• Length: 811
• Species: Danio rerio
• Alignment Length: 581
• Identity: 149/581 - (25%)
• Similarity: 264/581 - (45%)
• Gaps: 150/581 - (25%)

  Fly    47 LQCDPRCGHEVTIGR----RIGLYRFCGDIGRGNFSKVKLAVHQLTRD-----------KVAIKV 96
            :..|.|.|...:..:    ::|.|.....:|:|||:.||||.|::|:.           :||||:
Zfish     3 IMTDSRTGSHSSCAQARPLQVGFYEIIRTLGKGNFAVVKLARHKVTKTQAITTFYFIFMQVAIKI 67

  Fly    97 VDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGP 161
            :|..|  |::..|..:..|:..::.::||:|::|::|:||...:|:|||:.:.||:::::|..|.
Zfish    68 IDKTR--LNSANLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVTEYAKNGEMFDYLTSNGR 130

  Fly   162 LREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTF 226
            :.|..|.....|:|.||.:.|....||||:|.||:||.:...:|||||||..  ...|.:.|.|:
Zfish   131 MSENEARKKFWQILTAVDYCHRHHIVHRDLKTENLLLDANMNIKLADFGFGN--FYNAGEPLSTW 193

  Fly   227 CGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLS 291
            ||||||||||:|....|.|..:|:|:||::||.:|.|::||...::|.|:..:.:|.:.:|..:|
Zfish   194 CGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGDSLPALRQRVTEGRFRIPFFMS 258

  Fly   292 LPCIRLIQRILIHIPAQRPTIDDMLNSQFV----TCP--KLSADLMQWEIN--QHTKPVK----- 343
            ..|..||:::|:..||:|.||..:...:::    :.|  .||..|..:..|  .:::||.
Zfish   259 QDCENLIRKMLVVDPAKRITIAQIKQHRWMLADPSAPHQTLSLSLTDYNSNLGDYSEPVLGIMQT 323

  Fly   344 --------------------RSIFWV---RSKSHRLRKSA------SLRDRYAEVVKKPAISMNT 379
                                .:|:::   |.|.||.::.:      :.|.|.|.....|.:.|
Zfish   324 LGIDRQRTVESLQNSSYNHFSAIYYLLLERVKEHRSQQISRQCGAWNQRSRTASDSSTPEVIM-- 386

  Fly   380 RQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFC---GSLKKKVTPMETEP 441
             :..:.|           .....||::::..|..:|         |.|   |..::.|.|:|
Zfish   387 -ESSDSF-----------RNSAFPVATKVNAPIHSE---------MECEQGGLFQRVVCPVE--- 427

  Fly   442 EKQLANGGQSIGSAKINP--WNVEVAEDCPL-------FKNYDAETGSCVM------LPTNTEDL 491
                         |.:|.  ||..::.:..|       .:.:|.|....::      ||:.|
Zfish   428 -------------ASLNGLLWNRSISPNSLLETTISEEVRPHDLEEEEGILQVQPPHLPSTT--- 476

  Fly   492 SQLGALEFEARQILAEL-------------------GLTSEMLI--NARQSGPRSDIIGAY 531
                    ..|..|||:                   |.:|:..:  ::..:.|.|.::|.:
Zfish   477 --------SRRHTLAEVSTSRFHQCSPPCIVVSPSDGASSDSCLKSSSNTNPPLSPVVGDF 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	99/268 (37%)
sik1	NP_001119855.1	STKc_SIK	25..288	CDD:270973	98/266 (37%)
		UBA_SIK1	309..358	CDD:270591	6/48 (13%)