DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4629 and Brsk1

DIOPT Version :9

Sequence 1:	NP_608564.3	Gene:	CG4629 / 33284	FlyBaseID:	FBgn0031299	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001120809.1	Gene:	Brsk1 / 499073	RGDID:	1563268	Length:	778	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	90/300 - (30%)
Similarity:	152/300 - (50%)	Gaps:	38/300 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PHPPPLTTTTTPLTICQPPPPTPPYQRLTKALQCDPRCGHEVTIGRRIGLYRFCGDIGRGNFSKV 80
            |||.|            .||....|                      :|.||....:|:|....|
  Rat    18 PHPHP------------HPPQHAQY----------------------VGPYRLEKTLGKGQTGLV 48

  Fly    81 KLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVETLGRVYLVTE 145
            ||.||.:|..|||:|:|  :|..|....|..:..|||.|:.:.||::|:|.:|.|....:|||.|
  Rat    49 KLGVHCITGQKVAVKIV--NREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE 111

  Fly   146 WIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFG 210
            .:.||||::::.:.|.|....|....:|::.|:...||....|||:|.||:||..::.:::||||
  Rat   112 HVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFG 176

  Fly   211 FSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGL 275
            .::  :...:..|:|.||||.||.||:...:.|.|...|:|:.|::|:.::||.:||....:..|
  Rat   177 MAS--LQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQL 239

  Fly   276 KAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDM 315
            ...:.:|.:.:|..:...|..|::.::...|.:|.:::.:
  Rat   240 LEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQI 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	83/252 (33%)
CG4629	NP_608564.3	S_TKc	66..321	CDD:214567	82/249 (33%)
Brsk1	NP_001120809.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		6/22 (27%)
		STKc_BRSK1_2	32..285	CDD:270983	83/251 (33%)
		S_TKc	34..284	CDD:214567	82/249 (33%)
		UBA_BRSK	314..367	CDD:270525
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	719..778
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910