Protein Alignment CG4629 and sik3

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_073778929.1
• Gene: sik3 / 393513
• ZFINID: ZDB-GENE-140106-203
• Length: 1238
• Species: Danio rerio
• Alignment Length: 601
• Identity: 174/601 - (28%)
• Similarity: 277/601 - (46%)
• Gaps: 89/601 - (14%)

  Fly     5 ATVKVTSAATPPHPPPLTTTTTPLTICQPPPPTP---PYQRLTKALQCDPRCGHEVTIGRRIGLY 66
            |.|...:||....|.|......|....|..|.:.   |....:.|..|.|...       |:|.|
Zfish     2 AAVSSGAAAAAGIPNPNPNRERPQQQQQQQPASAALHPGAHRSAAAACRPPLA-------RVGYY 59

  Fly    67 RFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLF 131
            .....||:|||:.||||.|.:|:.|||||:|  |:..||.:.|:.:..|:..::.:.||:|:||:
Zfish    60 EMERTIGKGNFAVVKLATHMITKAKVAIKIV--DKTQLDDENLKKIFREVQIMKMLRHPHIIRLY 122

  Fly   132 EVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENV 196
            :|:||...:|||||:..|||:::|:...|.:.|..|....||::.||...|....||||:||||:
Zfish   123 QVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSIVHRDLKAENL 187

  Fly   197 LLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMV 261
            ||.....:|:||||||.....|  |.|.|:||||||||||||....|.|..||:|:||::||.:|
Zfish   188 LLDHNLNIKIADFGFSNLFSRG--QLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLV 250

  Fly   262 VGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFV----- 321
            .|.:||...|:..|:|.:|.|.:.:|..:|..|..||:.:||..|::|.:::.:..::::
Zfish   251 CGALPFDGSTLQNLRARVLSGKFRIPFFMSTDCEYLIRHMLILEPSRRLSMEQICKNKWMRQGDP 315

  Fly   322 --TCPKLSADLMQWEINQHTKPVKRSIFWVRSK---------------------------SHRLR 357
              ...:|..:..|.::.:.|:.:...:....::                           |.:|:
Zfish   316 DPEFDRLIVECEQVKVERETELINEQVLMAMAEMGFDRERTLQSLHADSYDHYSATYSLLSDKLK 380

  Fly   358 KSASL-------RDRYAEVVKKPAISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTE 415
            :..:|       |..|....:..|:||...|...:..:|  |.:|....:.:. |.:.:||....
Zfish   381 RHKNLCVAPPTPRPLYPLQDQSNAVSMTVPQVQLINPEN--QIVETDGPMALD-SDEGEEPSPEA 442

  Fly   416 QAKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGS 480
            .|     ||:   |:::....: .:|..::....|     |:.|....||...| |.........
Zfish   443 MA-----RYL---SMRRHTVGV-PDPRAEMQEDLQ-----KLAPGFPRVAPQAP-FPPLMPALAQ 492

  Fly   481 CVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGP----RSDIIGAYRIVVNRLQKQ 541
            ..::||.:....|  .||::.:.:|....|   .|:|.  .||    .||  |...|   :|..|
Zfish   493 MQLMPTPSLQPGQ--QLEYKEQSLLQPPTL---QLLNG--MGPLGRRASD--GGANI---QLHTQ 545

  Fly   542 SWLARKHVEMALHSEP 557
            ..|.|...:..|.:.|
Zfish   546 QLLKRPRGQSPLVTSP 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	109/257 (42%)
sik3	XP_073778929.1	None