Protein Alignment CG4629 and Melk

DIOPT Version :9

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001382535.1
• Gene: Melk / 362510
• RGDID: 1308974
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 166/663 - (25%)
• Similarity: 263/663 - (39%)
• Gaps: 216/663 - (32%)

  Fly    66 YRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRL 130
            |.....||.|.|:|||||.|.||.:.||||::|.:..|.|   |..:.:||..|:.:.|.:|.:|
  Rat    11 YELYETIGTGGFAKVKLACHILTGEMVAIKIMDKNALGSD---LPRVKTEIDALKNLRHQHICQL 72

  Fly   131 FEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAEN 195
            :.|:||..::::|.|:..||||:::|.....|.|.....:.:|:|.||.::||.||.|||:|.||
  Rat    73 YHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVIFRQILSAVAYVHSQGYAHRDLKPEN 137

  Fly   196 VLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFM 260
            :|.....:|||.|||...:.....:..|.|.|||..||||||.....|:|:..|||::|||||.:
  Rat   138 LLFDENHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVL 202

  Fly   261 VVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFV---- 321
            :.|.:||....:..|...|::|.|.:|..||...|.|:|::|...|.:|.::.::||..::
  Rat   203 MCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKRRISMKNLLNHPWILQDY 267

  Fly   322 TCPKLSADLMQW---------------EINQHTKPVKRSI-----FW----------------VR 350
            :||      ::|               |::.|.:..::::     .|                .|
  Rat   268 SCP------IEWQSKASLTHLDEDCITELSVHHRNSRQTMEDLISSWQYDHLTATYLLLLAKKAR 326

  Fly   351 SKSHRLR---------------KSASLRDRYAEVVKKPAISMNTRQQD--------EMFVQNFLQ 392
            .|..||:               |:.||.|            |:|....        |:...|.|.
  Rat   327 GKPARLQLLSFSGGTTSTTPKSKNLSLED------------MSTSGDSCVAGLIDYELCEDNLLA 379

  Fly   393 P---------IEMGH---ELLVPV-----SSQLKE------------------------PQSTEQ 416
            |         .|..|   |...||     :::||:                        |.|..|
  Rat   380 PQTPQFTKHWAESNHVECESPTPVVCRALANKLKDKENVCTPKSSVKNQEQFVFSEPKIPVSRNQ 444

  Fly   417 AKR-------------------------------------------PTRRYMFCGSLKKKVTP-- 436
            .||                                           |.||   |.|::..:..
  Rat   445 YKREILTSPTQFTAPAKARTQCLRETQVRTPVNSAGADTLTTNVISPERR---CRSMEVDLNQAH 506

  Fly   437 METEPEKQLANGGQSI-----------------GSAKINPWNVEVAEDCPLFKNYDAETGSCV-- 482
            ||..|:::..|...|:                 ||||..|...::        :|:..|...|
  Rat   507 MEDTPKRKGTNVFGSLERGLDKVLTALTRNKKKGSAKDGPRRRKL--------HYNVTTTRLVNP 563

  Fly   483 ---------MLPTNTEDLSQLG-ALEFEARQILAELGLTSEMLINARQSGPRSDIIGAYRIVVNR 537
                     :||....|..|.| .|:.:.:....::.:..|:.:...|   |.|::|..|   .|
  Rat   564 DQLLNEIMAILPKKNVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQ---RPDVVGIRR---QR 622

  Fly   538 LQKQSWLARKHVE 550
            |:..:|:.::.||
  Rat   623 LKGDAWVYKRLVE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	99/254 (39%)
		S_TKc	66..321	CDD:214567	99/254 (39%)
Melk	NP_001382535.1	STKc_MELK	7..263	CDD:270980	99/254 (39%)
		UBA_MELK	281..332	CDD:270526	5/50 (10%)
		MELK_C	547..641	CDD:213383	20/103 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910